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Amicus Therapeutics
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Overview Fund Activity

281 hedge funds and large institutions have $2.53B invested in Amicus Therapeutics in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 113 increasing their positions, 86 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
281
Holders Change
-5
Holders Change %
-1.75%
% of All Funds
3.82%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
41
Increased
113
Reduced
86
Closed
41
Calls
$3.21M
Puts
$5.05M
Net Calls
-$1.84M
Net Calls Change
-$1.73M

Top Buyers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
$24.4M
2
Millennium Management
Millennium Management
New York
$27.4M
3
RG
Redmile Group
California
$77.8M
4
Bank of America
Bank of America
North Carolina
$45.7M
5
Two Sigma Investments
Two Sigma Investments
New York
$11.4M

Top Sellers

1
Fiera Capital (Canada)
Fiera Capital (Canada)
Quebec, Canada
$0
2
PA
Perceptive Advisors
New York
$175M
3
ACA
Avoro Capital Advisors
New York
$167M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$39.9M
5
State Street
State Street
Massachusetts
$77.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
AAP
276
Arax Advisory Partners
Colorado
$580 +$368 +45 +173%
BIG
277
Brooklyn Investment Group
New York
$515 +$515 +63 New
SW
278
SVB Wealth
Massachusetts
$359 +$359 +44 New
HNB
279
Huntington National Bank
Ohio
$326 -$2.41K -296 -88%
WA
280
WPG Advisers
Maryland
$139 – – –
Norges Bank
281
Norges Bank
Norway
– -$29M -3,082,036 Closed
Fiera Capital (Canada)
282
Fiera Capital (Canada)
Quebec, Canada
– -$28.6M -3,037,248 Closed
Neuberger Berman Group
283
Neuberger Berman Group
New York
– -$5.29M -561,141 Closed
NICM
284
Neo Ivy Capital Management
New York
– -$3.73M -395,745 Closed
HP
285
HealthInvest Partners
Sweden
– -$3.08M -326,840 Closed
EIM
286
Essex Investment Management
Massachusetts
– -$2.18M -231,214 Closed
GLA
287
Great Lakes Advisors
Illinois
– -$1.68M -178,477 Closed
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
288
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
– -$1.65M -175,500 Closed
BCI
289
Brinker Capital Investments
Pennsylvania
– -$798K -84,693 Closed
OPS
290
Orion Portfolio Solutions
Nebraska
– -$798K -84,693 Closed
Walleye Capital
291
Walleye Capital
New York
– -$419K -44,516 Closed
TCM
292
Teza Capital Management
Illinois
– -$372K -39,458 Closed
SCA
293
Snowden Capital Advisors
New York
– -$325K -34,508 Closed
SC
294
Syon Capital
California
– -$285K -30,255 Closed
OAM
295
Oppenheimer Asset Management
New York
– -$219K -23,260 Closed
Mariner
296
Mariner
Kansas
– -$206K -21,838 Closed
BHCM
297
Brevan Howard Capital Management
Jersey
– -$172K -18,266 Closed
AC
298
AXQ Capital
New Jersey
– -$171K -18,126 Closed
AF
299
Avanza Fonder
Sweden
– -$157K -16,652 Closed
I
300
InceptionR
California
– -$130K -13,778 Closed
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