|
1
|
RA Capital Management
Boston,
Massachusetts
|
$209M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$118M
|
-$17.8M
|
-754,564
|
-13%
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$109M
|
-$25.9K
|
-1,094
|
-0%
|
|
|
4
|
|
$79.1M
|
+$1.79M
|
+75,561
|
+2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$64.8M
|
+$11.8M
|
+497,048
|
+22%
|
|
|
6
|
Logos Global Management
San Francisco,
California
|
$49M
|
+$21.3M
|
+900,000
|
+74%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$47M
|
–
|
–
|
–
|
|
|
8
|
Samsara BioCapital
Palo Alto,
California
|
$36.3M
|
-$71
|
-3
|
-0%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$33.8M
|
-$16.9M
|
-716,375
|
-33%
|
|
|
10
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$25.5M
|
–
|
–
|
–
|
|
|
11
|
|
$23.2M
|
–
|
–
|
–
|
|
|
12
|
Lone Pine Capital
Greenwich,
Connecticut
|
$18.6M
|
–
|
–
|
–
|
|
|
13
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$11.7M
|
+$74.5K
|
+3,150
|
+0.6%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$11.4M
|
+$1.08M
|
+45,722
|
+10%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$7.09M
|
+$419K
|
+17,724
|
+6%
|
|
|
16
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$6.79M
|
–
|
–
|
–
|
|
|
17
|
Charles Schwab
San Francisco,
California
|
$5.23M
|
+$1.42M
|
+60,228
|
+36%
|
|
|
18
|
|
$4.51M
|
+$728K
|
+30,810
|
+19%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$4.24M
|
+$283K
|
+11,950
|
+7%
|
|
|
20
|
|
$4.23M
|
+$1.75M
|
+73,886
|
+68%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.47M
|
–
|
–
|
–
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$3.06M
|
-$279K
|
-11,789
|
-8%
|
|
|
23
|
Bank of New York Mellon
New York
|
$2.62M
|
+$363K
|
+15,373
|
+16%
|
|
|
24
|
Parametric Portfolio Associates
Seattle,
Washington
|
$2.31M
|
+$196K
|
+8,289
|
+9%
|
|
|
25
|
Millennium Management
New York
|
$2.24M
|
-$3.81K
|
-161
|
-0.2%
|
|
