|
1
|
RA Capital Management
Boston,
Massachusetts
|
$315M
|
–
|
–
|
–
|
|
|
2
|
Cormorant Asset Management
Boston,
Massachusetts
|
$156M
|
+$47M
|
+1,080,627
|
+32%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$144M
|
+$100M
|
+2,302,821
|
+127%
|
|
|
4
|
|
$92M
|
+$51.2M
|
+1,176,982
|
+81%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$70.7M
|
+$11M
|
+253,367
|
+14%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$53.2M
|
+$24.7M
|
+567,182
|
+59%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$52.2M
|
-$15.1M
|
-346,365
|
-19%
|
|
|
8
|
Samsara BioCapital
Palo Alto,
California
|
$49.5M
|
-$3.21M
|
-73,634
|
-5%
|
|
|
9
|
Logos Global Management
San Francisco,
California
|
$48.9M
|
+$9.87M
|
+226,812
|
+19%
|
|
|
10
|
Perceptive Advisors
New York
|
$43.6M
|
–
|
–
|
–
|
|
|
11
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$38.4M
|
+$26.1M
|
+600,000
|
+120%
|
|
|
12
|
Janus Henderson Group
London,
|
$37.8M
|
-$15.9M
|
-364,633
|
-25%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$29.9M
|
+$28.1M
|
+645,047
|
+307%
|
|
|
14
|
Lone Pine Capital
Greenwich,
Connecticut
|
$27.9M
|
+$34.8M
|
+800,000
|
New
|
|
|
15
|
|
$17.4M
|
+$21.8M
|
+500,000
|
New
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$10.3M
|
+$1.53M
|
+35,165
|
+14%
|
|
|
17
|
Great Point Partners
Greenwich,
Connecticut
|
$8.25M
|
+$10.3M
|
+236,400
|
New
|
|
|
18
|
Marshall Wace North America
New York
|
$7.81M
|
+$9.74M
|
+223,653
|
New
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$7.15M
|
+$808K
|
+18,565
|
+10%
|
|
|
20
|
Millennium Management
New York
|
$6.99M
|
+$8.72M
|
+200,328
|
New
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$5.23M
|
+$6.52M
|
+149,825
|
New
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$4.42M
|
+$1.2M
|
+27,609
|
+28%
|
|
|
23
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$4.29M
|
-$5.21M
|
-119,578
|
-49%
|
|
|
24
|
|
$4.21M
|
+$5.25M
|
+120,698
|
New
|
|
|
25
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$3.97M
|
+$4.95M
|
+113,792
|
New
|
|
