|
1
|
RA Capital Management
Boston,
Massachusetts
|
$224M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$145M
|
+$23.1M
|
+857,895
|
+17%
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$118M
|
+$42.7K
|
+1,589
|
+0%
|
|
|
4
|
|
$83M
|
+$1.2M
|
+44,549
|
+1%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$57.1M
|
+$2.77M
|
+102,994
|
+5%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$54.1M
|
+$8.14M
|
+302,780
|
+16%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$50.4M
|
–
|
–
|
–
|
|
|
8
|
Samsara BioCapital
Palo Alto,
California
|
$39M
|
–
|
–
|
–
|
|
|
9
|
Logos Global Management
San Francisco,
California
|
$30.2M
|
-$5.24M
|
-195,000
|
-14%
|
|
|
10
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$27.4M
|
–
|
–
|
–
|
|
|
11
|
|
$24.9M
|
–
|
–
|
–
|
|
|
12
|
Lone Pine Capital
Greenwich,
Connecticut
|
$19.9M
|
–
|
–
|
–
|
|
|
13
|
Janus Henderson Group
London,
|
$19.3M
|
-$1.86M
|
-69,378
|
-8%
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$12.4M
|
+$26.8K
|
+996
|
+0.2%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$11.1M
|
+$359K
|
+13,360
|
+3%
|
|
|
16
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$7.29M
|
+$4.56M
|
+169,688
|
+138%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$7.17M
|
-$242K
|
-8,998
|
-3%
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$5.3M
|
-$4.21M
|
-156,596
|
-42%
|
|
|
19
|
Marshall Wace North America
New York
|
$4.6M
|
–
|
–
|
–
|
|
|
20
|
Opaleye Management
Boston,
Massachusetts
|
$4.26M
|
+$4.59M
|
+171,000
|
New
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$4.12M
|
+$210K
|
+7,831
|
+5%
|
|
|
22
|
|
$4.08M
|
-$461K
|
-17,151
|
-9%
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.73M
|
–
|
–
|
–
|
|
|
24
|
|
$3.67M
|
+$790K
|
+29,387
|
+25%
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$3.5M
|
+$216K
|
+8,025
|
+6%
|
|
