|
1
|
RA Capital Management
Boston,
Massachusetts
|
$253M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$139M
|
+$30.8M
|
+854,320
|
+21%
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$132M
|
+$9.38M
|
+260,000
|
+6%
|
|
|
4
|
|
$92.2M
|
+$23.6M
|
+654,826
|
+25%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$61.4M
|
+$24.1M
|
+668,281
|
+44%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$56.7M
|
–
|
–
|
–
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$52.4M
|
+$36.7M
|
+1,016,220
|
+119%
|
|
|
8
|
Samsara BioCapital
Palo Alto,
California
|
$43.9M
|
+$5.3M
|
+147,000
|
+10%
|
|
|
9
|
Logos Global Management
San Francisco,
California
|
$39.5M
|
+$361K
|
+10,000
|
+0.7%
|
|
|
10
|
Perceptive Advisors
New York
|
$35M
|
–
|
–
|
–
|
|
|
11
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$30.8M
|
–
|
–
|
–
|
|
|
12
|
|
$28M
|
+$18M
|
+500,000
|
+100%
|
|
|
13
|
Janus Henderson Group
London,
|
$23.7M
|
-$9.69M
|
-268,486
|
-24%
|
|
|
14
|
Lone Pine Capital
Greenwich,
Connecticut
|
$22.4M
|
–
|
–
|
–
|
|
|
15
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$14M
|
+$17.3M
|
+478,200
|
+2,289%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$12.1M
|
+$4.99M
|
+138,283
|
+47%
|
|
|
17
|
Wellington Management Group
Boston,
Massachusetts
|
$10.4M
|
-$40.6M
|
-1,126,606
|
-75%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$8.32M
|
+$3.33M
|
+92,156
|
+45%
|
|
|
19
|
Marshall Wace North America
New York
|
$5.18M
|
-$1.4M
|
-38,778
|
-17%
|
|
|
20
|
|
$5.07M
|
+$2.17M
|
+60,188
|
+50%
|
|
|
21
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$4.46M
|
+$1.64M
|
+45,469
|
+40%
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$4.41M
|
+$1.12M
|
+31,026
|
+25%
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$4.2M
|
–
|
–
|
–
|
|
|
24
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$4.12M
|
–
|
–
|
–
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$3.72M
|
+$2.46M
|
+68,232
|
+106%
|
|
