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Edgewise Therapeutics

192 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 68 increasing their positions, 63 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

88% more call options, than puts

Call options by funds: $61.6M | Put options by funds: $32.7M

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

6.09% more ownership

Funds ownership: 104.55%110.64% (+6.1%)

8% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 63

4% less funds holding

Funds holding: 200192 (-8)

12% less capital invested

Capital invested by funds: $2.64B → $2.32B (-$321M)

16% less first-time investments, than exits

New positions opened: 32 | Existing positions closed: 38

Holders
192
Holders Change
-8
Holders Change %
-4%
% of All Funds
2.57%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.13%
New
32
Increased
68
Reduced
63
Closed
38
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M
Name Holding Trade Value Shares
Change
Change in
Stake
Squarepoint
101
Squarepoint
New York
$1.01M +$509K +19,398 +74%
MIM
102
MetLife Investment Management
New Jersey
$965K -$19.1K -729 -2%
Mirae Asset Global ETFs Holdings
103
Mirae Asset Global ETFs Holdings
Hong Kong
$963K +$64.6K +2,463 +6%
SEI Investments
104
SEI Investments
Pennsylvania
$945K -$242K -9,216 -18%
UOC
105
UBS O'Connor
Illinois
$880K +$1.05M +40,014 New
Skandinaviska Enskilda Banken (SEB)
106
Skandinaviska Enskilda Banken (SEB)
Sweden
$827K +$986K +37,591 New
EGM
107
Engineers Gate Manager
New York
$800K +$954K +36,358 New
CF
108
Corebridge Financial
Texas
$793K -$1.08K -41 -0.1%
California State Teachers Retirement System (CalSTRS)
109
California State Teachers Retirement System (CalSTRS)
California
$793K -$42.2K -1,610 -4%
Wells Fargo
110
Wells Fargo
California
$773K +$32.5K +1,240 +4%
Two Sigma Investments
111
Two Sigma Investments
New York
$770K -$2.54M -96,668 -73%
Verition Fund Management
112
Verition Fund Management
Connecticut
$764K -$306K -11,672 -25%
TD Asset Management
113
TD Asset Management
Ontario, Canada
$730K +$871K +33,200 New
FAM
114
Fred Alger Management
New York
$608K +$725K +27,635 New
Handelsbanken Fonder
115
Handelsbanken Fonder
Sweden
$480K
GT
116
Glenmede Trust
Pennsylvania
$480K -$2.89K -110 -0.5%
ProShare Advisors
117
ProShare Advisors
Maryland
$444K -$124K -4,725 -19%
ACM
118
ADAR1 Capital Management
Texas
$440K +$525K +20,000 New
CUAMC
119
China Universal Asset Management Company
China
$418K -$28.4K -1,084 -5%
GCM
120
Graham Capital Management
Connecticut
$375K -$35.9K -1,368 -7%
State Board of Administration of Florida Retirement System
121
State Board of Administration of Florida Retirement System
Florida
$371K
CWM
122
CIBC World Markets
New York
$359K +$428K +16,328 New
Walleye Capital
123
Walleye Capital
New York
$356K -$4.79M -182,484 -92%
PA
124
Profund Advisors
Maryland
$345K +$19.5K +742 +5%
PFSRSONJ
125
Police & Firemen's Retirement System of New Jersey
New Jersey
$340K

EWTX Hedge Fund Activity: Q1 2025 in Review

192 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q1 2025, worth a combined $2.32B — down 12% from $2.64B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of EWTX and 32 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 68 added.

The largest buyer was Perceptive Advisors, adding an estimated $101M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $33.9M sold.

  • 192 institutional investors held Edgewise Therapeutics (EWTX) as of Q1 2025, down from 200 in Q4 2024.
  • Funds reported $2.32B of Edgewise Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 32 funds opened new Edgewise Therapeutics positions in Q1 2025 and 38 closed out, a net change of -6 holders.
  • The largest Edgewise Therapeutics buyer in Q1 2025 was Perceptive Advisors, an estimated $101M added.
  • The largest Edgewise Therapeutics seller in Q1 2025 was Frazier Life Sciences Management, an estimated $33.9M sold.

Based on aggregated 13F filings for Q1 2025.