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ETNB

89bio
ETNB

Delisted

ETNB was delisted on the 29th of October, 2025.

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2 hedge funds and large institutions have $1.11M invested in 89bio in 2025 Q4 according to their latest regulatory filings, with 0 funds opening new positions, 0 increasing their positions, 0 reducing their positions, and 192 closing their positions.

New
Increased
Maintained
Reduced
Closed

99% less funds holding

Funds holding: 198 → 2 (-196)

100% less capital invested

Capital invested by funds: $2.27B → $1.11M (-$2.27B)

100% less funds holding in top 10

Funds holding in top 10: 11 → 0 (-11)

100% less first-time investments, than exits

New positions opened: 0 | Existing positions closed: 192

104.24% less ownership

Funds ownership: 104.3% → 0.06% (-104%)

Holders
2
Holders Change
-196
Holders Change %
-98.99%
% of All Funds
0.02%
Holding in Top 10
–
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-100%
% of All Funds
–
New
–
Increased
–
Reduced
–
Closed
192
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

No buyers this quarter

Top Sellers

Rank Fund Capital Flow
1
RCM
RA Capital Management
Massachusetts
-$292M
2
PCM
Pentwater Capital Management
Florida
-$173M
3
BlackRock
BlackRock
New York
-$152M
4
DTC
Deep Track Capital
Connecticut
-$138M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$134M
Name Holding Trade Value Shares
Change 		Change in
Stake
Nisa Investment Advisors
176
Nisa Investment Advisors
Missouri
– -$22.3K -1,518 Closed
MCM
177
MAI Capital Management
Ohio
– -$14.7K -1,000 Closed
LFG
178
Larson Financial Group
Missouri
– -$12.3K -838 Closed
CAL
179
Capital Advisors Ltd
Ohio
– -$12K -798 Closed
GI
180
GAMMA Investing
California
– -$11.7K -795 Closed
Optiver Holding
181
Optiver Holding
Netherlands
– -$9.79K -666 Closed
Daiwa Securities Group
182
Daiwa Securities Group
Japan
– -$7K -499 Closed
S
183
SignatureFD
Georgia
– -$4.54K -309 Closed
EWA
184
EverSource Wealth Advisors
Alabama
– -$4.32K -294 Closed
RIL
185
Rothschild Investment LLC
Illinois
– -$3.82K -260 Closed
EP
186
Essential Partners
California
– -$3.42K -233 Closed
PFBT
187
Parkside Financial Bank & Trust
Missouri
– -$2.65K -180 Closed
AF
188
Allworth Financial
California
– -$1.68K -114 Closed
AW
189
Avion Wealth
Texas
– -$1K -72 Closed
US Bancorp
190
US Bancorp
Minnesota
– -$721 -49 Closed
SAM
191
Smartleaf Asset Management
Massachusetts
– -$588 -40 Closed
SS
192
SBI Securities
Japan
– -$397 -27 Closed
QT
193
Quantbot Technologies
New York
– -$132 -9 Closed
ASN
194
Advisory Services Network
Georgia
– -$44 -3 Closed
4 5 6 7
8

ETNB Hedge Fund Activity: Q4 2025 in Review

2 of the 8,226 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q4 2025, worth a combined $1.11M — down 100% from $2.27B a quarter earlier.

Sellers outnumbered buyers: 192 funds closed out of ETNB and 0 opened new positions — a net loss of 192 holders — while 0 trimmed existing stakes and 0 added.

The largest seller was RA Capital Management, exiting entirely with an estimated $292M sold.

  • 2 institutional investors held 89bio (ETNB) as of Q4 2025, down from 198 in Q3 2025.
  • Funds reported $1.11M of 89bio stock for Q4 2025, down 100% quarter-over-quarter.
  • 0 funds opened new 89bio positions in Q4 2025 and 192 closed out, a net change of -192 holders.
  • The largest 89bio seller in Q4 2025 was RA Capital Management, an estimated $292M sold.

Based on aggregated 13F filings for Q4 2025.