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ETNB

89bio
ETNB

Delisted

ETNB was delisted on the 29th of October, 2025.

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145 hedge funds and large institutions have $1.08B invested in 89bio in 2023 Q1 according to their latest regulatory filings, with 60 funds opening new positions, 48 increasing their positions, 29 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 20

122% more call options, than puts

Call options by funds: $55.5M | Put options by funds: $25M

84% more capital invested

Capital invested by funds: $589M → $1.08B (+$492M)

66% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 29

37% more funds holding

Funds holding: 106 → 145 (+39)

3.15% more ownership

Funds ownership: 99.5% → 102.65% (+3.2%)

Holders
145
Holders Change
+39
Holders Change %
+36.79%
% of All Funds
2.31%
Holding in Top 10
3
Holding in Top 10 Change
+3
Holding in Top 10 Change %
% of All Funds
0.05%
New
60
Increased
48
Reduced
29
Closed
20
Calls
$55.5M
Puts
$25M
Net Calls
+$30.5M
Net Calls Change
+$25.5M

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$38.7M
2
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$35.6M
3
RCM
RA Capital Management
Massachusetts
+$32.1M
4
Federated Hermes
Federated Hermes
Pennsylvania
+$30.7M
5
SCM
Suvretta Capital Management
New York
+$28.8M

Top Sellers

Rank Fund Capital Flow
1
O
OrbiMed
New York
-$46.6M
2
DTC
Deep Track Capital
Connecticut
-$26.7M
3
CC
Commodore Capital
New York
-$9.65M
4
Walleye Capital
Walleye Capital
New York
-$6.11M
5
IC
Ikarian Capital
Texas
-$5.78M
Name Holding Trade Value Shares
Change 		Change in
Stake
ECM
51
ExodusPoint Capital Management
New York
$3.46M +$2.96M +227,089 New
Jane Street
52
Jane Street
New York
$3.33M +$1.53M +117,135 +116%
NM
53
Newtyn Management
New York
$3.05M -$1.43M -110,000 -35%
AAA
54
Affinity Asset Advisors
New York
$3.05M +$2.61M +200,000 New
GTC
55
Ghost Tree Capital
New York
$3.05M +$2.61M +200,000 New
Royal Bank of Canada
56
Royal Bank of Canada
Ontario, Canada
$3.04M +$108K +8,292 +4%
PMAM
57
Picton Mahoney Asset Management
Ontario, Canada
$3.01M +$1.12M +85,841 +77%
PHS
58
Pekin Hardy Strauss
Illinois
$2.84M -$108K -8,294 -4%
Hudson Bay Capital Management
59
Hudson Bay Capital Management
Connecticut
$2.62M +$2.24M +171,835 New
Simplex Trading
60
Simplex Trading
Illinois
$2.4M +$1.15M +88,017 +126%
TLP
61
Tri Locum Partners
New York
$2.39M +$2.05M +157,225 New
D.E. Shaw & Co
62
D.E. Shaw & Co
New York
$2.38M +$2.04M +156,503 New
Barclays
63
Barclays
United Kingdom
$2.33M -$3.34M -256,269 -63%
CS
64
Candriam SCA
Luxembourg
$2.24M +$2.09M +160,000 New
Squarepoint
65
Squarepoint
New York
$2.17M +$1.34M +103,076 +260%
UBS Group
66
UBS Group
Switzerland
$2.15M +$1.71M +131,005 +1,295%
RCAP
67
Resolute Capital Asset Partners
Colorado
$1.9M +$1.63M +125,000 New
RJFSA
68
Raymond James Financial Services Advisors
Florida
$1.66M +$80.7K +6,189 +6%
TCM
69
Tekla Capital Management
Massachusetts
$1.61M +$1.38M +105,898 New
Northern Trust
70
Northern Trust
Illinois
$1.55M +$486K +37,266 +58%
VCIM
71
Velan Capital Investment Management
Georgia
$1.5M +$1.28M +98,500 New
Dimensional Fund Advisors
72
Dimensional Fund Advisors
Texas
$1.36M +$241K +18,508 +26%
Connor, Clark & Lunn Investment Management (CC&L)
73
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.36M +$1.16M +89,339 New
State of Wisconsin Investment Board
74
State of Wisconsin Investment Board
Wisconsin
$1.21M – – –
1CM
75
1492 Capital Management
Wisconsin
$1.19M -$326 -25 -0%
1 2
3
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ETNB Hedge Fund Activity: Q1 2023 in Review

145 of the 6,276 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q1 2023, worth a combined $1.08B — up 84% from $589M a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new ETNB positions and 20 closed out — a net gain of 40 holders — while 48 added to existing stakes and 29 trimmed.

The largest buyer was State Street, adding an estimated $38.7M. The largest seller was OrbiMed, exiting entirely with an estimated $46.6M sold.

  • 145 institutional investors held 89bio (ETNB) as of Q1 2023, up from 106 in Q4 2022.
  • Funds reported $1.08B of 89bio stock for Q1 2023, up 84% quarter-over-quarter.
  • 60 funds opened new 89bio positions in Q1 2023 and 20 closed out, a net change of +40 holders.
  • The largest 89bio buyer in Q1 2023 was State Street, an estimated $38.7M added.
  • The largest 89bio seller in Q1 2023 was OrbiMed, an estimated $46.6M sold.

Based on aggregated 13F filings for Q1 2023.