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ETNB

89bio

Delisted

ETNB was delisted on the 29th of October, 2025.

184 hedge funds and large institutions have $1.58B invested in 89bio in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 80 increasing their positions, 56 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

43% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 56

39% more capital invested

Capital invested by funds: $1.14B → $1.58B (+$444M)

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

4.7% more ownership

Funds ownership: 105.72%110.42% (+4.7%)

6% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 33

1% less funds holding

Funds holding: 186184 (-2)

79% less call options, than puts

Call options by funds: $3.66M | Put options by funds: $17.4M

Holders
184
Holders Change
-2
Holders Change %
-1.08%
% of All Funds
2.42%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
31
Increased
80
Reduced
56
Closed
33
Calls
$3.66M
Puts
$17.4M
Net Calls
-$13.7M
Net Calls Change
-$9.12M
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$11.6M +$4.93M +595,237 +101%
UOWF
27
University of Wisconsin Foundation
Wisconsin
$11.3M
EMFAT
28
Emerald Mutual Fund Advisers Trust
Pennsylvania
$11.3M +$520K +62,840 +6%
Northern Trust
29
Northern Trust
Illinois
$11.1M +$389K +46,973 +4%
Charles Schwab
30
Charles Schwab
California
$10.4M +$648K +78,201 +8%
IHAM
31
Integral Health Asset Management
New York
$10.3M
Millennium Management
32
Millennium Management
New York
$9.45M +$4.22M +510,020 +113%
RAM
33
Readystate Asset Management
Illinois
$8.86M +$1.8M +216,907 +32%
EAM
34
Erste Asset Management
Austria
$8.68M
ACM
35
ADAR1 Capital Management
Texas
$8.6M +$594K +71,763 +9%
CS
36
Candriam SCA
Luxembourg
$7.52M -$543K -65,612 -8%
N
37
Nuveen
North Carolina
$6.27M -$3.29M -397,130 -38%
Alyeska Investment Group
38
Alyeska Investment Group
Illinois
$5.67M -$2.28M -275,254 -32%
Raymond James Financial
39
Raymond James Financial
Florida
$5.61M +$1.57M +189,311 +50%
Fidelity Investments
40
Fidelity Investments
Massachusetts
$5.59M -$1M -121,007 -18%
Renaissance Technologies
41
Renaissance Technologies
New York
$5.04M +$75.3K +9,100 +2%
IAM
42
Infinitum Asset Management
Florida
$4.91M
Barclays
43
Barclays
United Kingdom
$4.8M -$2.8M -338,149 -41%
UBS AM
44
UBS AM
Illinois
$3.84M +$1.02M +122,612 +46%
SSA
45
Schonfeld Strategic Advisors
New York
$3.76M +$3.17M +383,188 New
VC
46
Vivo Capital
California
$3.7M
Wellington Management Group
47
Wellington Management Group
Massachusetts
$3.61M +$969K +117,074 +47%
Bank of New York Mellon
48
Bank of New York Mellon
New York
$3.43M +$328K +39,656 +13%
UBS Group
49
UBS Group
Switzerland
$3.43M +$1.21M +146,238 +72%
PAM
50
Panagora Asset Management
Massachusetts
$3.24M -$824K -99,511 -23%

ETNB Hedge Fund Activity: Q2 2025 in Review

184 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in 89bio (ETNB) for Q2 2025, worth a combined $1.58B — up 39% from $1.14B a quarter earlier.

Sellers outnumbered buyers: 33 funds closed out of ETNB and 31 opened new positions — a net loss of 2 holders — while 56 trimmed existing stakes and 80 added.

The largest buyer was Holocene Advisors, opening a new position worth an estimated $25.4M. The largest seller was Logos Global Management, exiting entirely with an estimated $18.2M sold.

  • 184 institutional investors held 89bio (ETNB) as of Q2 2025, down from 186 in Q1 2025.
  • Funds reported $1.58B of 89bio stock for Q2 2025, up 39% quarter-over-quarter.
  • 31 funds opened new 89bio positions in Q2 2025 and 33 closed out, a net change of -2 holders.
  • The largest 89bio buyer in Q2 2025 was Holocene Advisors, an estimated $25.4M added.
  • The largest 89bio seller in Q2 2025 was Logos Global Management, an estimated $18.2M sold.

Based on aggregated 13F filings for Q2 2025.