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Enanta Pharmaceuticals

132 hedge funds and large institutions have $338M invested in Enanta Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 49 increasing their positions, 33 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

131% more call options, than puts

Call options by funds: $496K | Put options by funds: $215K

48% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 33

14% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 21

0.82% more ownership

Funds ownership: 91.43%92.26% (+0.82%)

1% more funds holding

Funds holding: 131132 (+1)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

19% less capital invested

Capital invested by funds: $416M → $338M (-$78M)

Holders
132
Holders Change
+1
Holders Change %
+0.76%
% of All Funds
1.62%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
49
Reduced
33
Closed
21
Calls
$496K
Puts
$215K
Net Calls
+$281K
Net Calls Change
-$1.78M
Name Holding Trade Value Shares
Change
Change in
Stake
TPWA
126
Twin Peaks Wealth Advisors
California
$76 +$80 +6 New
ASN
127
Advisory Services Network
Georgia
$51 +$54 +4 New
WPA
128
Wealth Preservation Advisors
Tennessee
$25 +$27 +2 New
HFS
129
Hughes Financial Services
Virginia
$13 +$13 +1 New
SIC
130
SJS Investment Consulting
Ohio
$13 +$13 +1 New
TFM
131
TFC Financial Management
Massachusetts
$13 +$13 +1 New
Point72 Asset Management
132
Point72 Asset Management
Connecticut
-$6.92M -438,939 Closed
Two Sigma Advisers
133
Two Sigma Advisers
New York
-$2.26M -143,300 Closed
SCM
134
Stonepine Capital Management
Oregon
-$1.58M -100,000 Closed
PP
135
PDT Partners
New York
-$1.09M -69,197 Closed
Arrowstreet Capital
136
Arrowstreet Capital
Massachusetts
-$832K -52,728 Closed
SFI
137
Susquehanna Fundamental Investments
Pennsylvania
-$795K -50,434 Closed
Assenagon Asset Management
138
Assenagon Asset Management
Luxembourg
-$723K -45,877 Closed
American Century Companies
139
American Century Companies
Missouri
-$532K -33,764 Closed
Hudson Bay Capital Management
140
Hudson Bay Capital Management
Connecticut
-$473K -30,000 Closed
A
141
AlphaQuest
New York
-$224K -14,178 Closed
VF
142
Virtu Financial
New York
-$220K -13,967 Closed
JF
143
Jump Financial
Illinois
-$219K -13,900 Closed
JG
144
Jain Global
New York
-$198K -12,543 Closed
KWM
145
Kingsview Wealth Management
Oregon
-$168K -10,653 Closed
Canada Pension Plan Investment Board
146
Canada Pension Plan Investment Board
Ontario, Canada
-$140K -8,900 Closed
SFCM
147
Seven Fleet Capital Management
California
-$35.8K -2,270 Closed
AB
148
Amalgamated Bank
New York
-$14K -857 Closed
Daiwa Securities Group
149
Daiwa Securities Group
Japan
-$2K -96 Closed
PA
150
Parallel Advisors
California
-$804 -51 Closed

ENTA Hedge Fund Activity: Q1 2026 in Review

132 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Enanta Pharmaceuticals (ENTA) for Q1 2026, worth a combined $338M — down 19% from $416M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new ENTA positions and 21 closed out — a net gain of 3 holders — while 49 added to existing stakes and 33 trimmed.

The largest buyer was Spruce Street Capital, adding an estimated $7.28M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $6.92M sold.

  • 132 institutional investors held Enanta Pharmaceuticals (ENTA) as of Q1 2026, up from 131 in Q4 2025.
  • Funds reported $338M of Enanta Pharmaceuticals stock for Q1 2026, down 19% quarter-over-quarter.
  • 24 funds opened new Enanta Pharmaceuticals positions in Q1 2026 and 21 closed out, a net change of +3 holders.
  • The largest Enanta Pharmaceuticals buyer in Q1 2026 was Spruce Street Capital, an estimated $7.28M added.
  • The largest Enanta Pharmaceuticals seller in Q1 2026 was Point72 Asset Management, an estimated $6.92M sold.

Based on aggregated 13F filings for Q1 2026.