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Enanta Pharmaceuticals

107 hedge funds and large institutions have $139M invested in Enanta Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 34 increasing their positions, 43 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,444% more call options, than puts

Call options by funds: $409K | Put options by funds: $9K

36% more capital invested

Capital invested by funds: $103M → $139M (+$36.6M)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

1.05% less ownership

Funds ownership: 87.32%86.28% (-1%)

2% less funds holding

Funds holding: 109107 (-2)

12% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 17

21% less repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 43

Holders
107
Holders Change
-2
Holders Change %
-1.83%
% of All Funds
1.41%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
15
Increased
34
Reduced
43
Closed
17
Calls
$409K
Puts
$9K
Net Calls
+$400K
Net Calls Change
+$444K
Name Holding Trade Value Shares
Change
Change in
Stake
FCM
1
Farallon Capital Management
California
$16M
KAM
2
Krensavage Asset Management
New York
$16M -$12.9K -2,142 -0.1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$14.9M -$185K -30,761 -2%
BlackRock
4
BlackRock
New York
$14M -$1.03M -171,764 -9%
Millennium Management
5
Millennium Management
New York
$11M +$672K +111,661 +8%
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$6.55M
Marshall Wace
7
Marshall Wace
United Kingdom
$6.48M +$39.2K +6,522 +0.8%
SCM
8
Stonepine Capital Management
Oregon
$4.57M +$80.1K +13,324 +2%
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$3.96M +$3.15M +523,743 New
Geode Capital Management
10
Geode Capital Management
Massachusetts
$3.67M -$50.6K -8,408 -2%
State Street
11
State Street
Massachusetts
$3.56M +$89.5K +14,876 +3%
Renaissance Technologies
12
Renaissance Technologies
New York
$3.55M +$35.5K +5,900 +1%
AQR Capital Management
13
AQR Capital Management
Connecticut
$2.99M +$235K +39,001 +11%
Morgan Stanley
14
Morgan Stanley
New York
$2.17M -$1.2M -198,965 -41%
D.E. Shaw & Co
15
D.E. Shaw & Co
New York
$2.13M -$608K -101,044 -26%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$2.1M -$28K -4,662 -2%
TI
17
Trexquant Investment
Connecticut
$2M -$151K -25,101 -9%
Northern Trust
18
Northern Trust
Illinois
$1.9M -$417K -69,298 -22%
Jacobs Levy Equity Management
19
Jacobs Levy Equity Management
New Jersey
$1.45M -$449K -74,698 -28%
SCM
20
Sio Capital Management
New York
$1.35M +$10.6K +1,770 +1%
Charles Schwab
21
Charles Schwab
California
$1.24M +$29.1K +4,846 +3%
UBS AM
22
UBS AM
Illinois
$1.13M -$62.1K -10,319 -6%
Two Sigma Advisers
23
Two Sigma Advisers
New York
$1.01M -$75.2K -12,500 -9%
JP Morgan Chase
24
JP Morgan Chase
New York
$986K -$22.7K -3,769 -3%
TCM
25
Tang Capital Management
California
$958K

ENTA Hedge Fund Activity: Q2 2025 in Review

107 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Enanta Pharmaceuticals (ENTA) for Q2 2025, worth a combined $139M — up 36% from $103M a quarter earlier.

Sellers outnumbered buyers: 17 funds closed out of ENTA and 15 opened new positions — a net loss of 2 holders — while 43 trimmed existing stakes and 34 added.

The largest buyer was Janus Henderson Group, opening a new position worth an estimated $3.15M. The largest seller was Morgan Stanley, cutting an estimated $1.2M.

  • 107 institutional investors held Enanta Pharmaceuticals (ENTA) as of Q2 2025, down from 109 in Q1 2025.
  • Funds reported $139M of Enanta Pharmaceuticals stock for Q2 2025, up 36% quarter-over-quarter.
  • 15 funds opened new Enanta Pharmaceuticals positions in Q2 2025 and 17 closed out, a net change of -2 holders.
  • The largest Enanta Pharmaceuticals buyer in Q2 2025 was Janus Henderson Group, an estimated $3.15M added.
  • The largest Enanta Pharmaceuticals seller in Q2 2025 was Morgan Stanley, an estimated $1.2M sold.

Based on aggregated 13F filings for Q2 2025.