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Enanta Pharmaceuticals

121 hedge funds and large institutions have $227M invested in Enanta Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 32 increasing their positions, 43 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more call options, than puts

Call options by funds: $3.7M | Put options by funds: $870K

127% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 11

63% more capital invested

Capital invested by funds: $139M → $227M (+$87.7M)

13% more funds holding

Funds holding: 107121 (+14)

2.57% more ownership

Funds ownership: 86.28%88.84% (+2.6%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

26% less repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 43

Holders
121
Holders Change
+14
Holders Change %
+13.08%
% of All Funds
1.59%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
25
Increased
32
Reduced
43
Closed
11
Calls
$3.7M
Puts
$870K
Net Calls
+$2.83M
Net Calls Change
+$2.43M
Name Holding Trade Value Shares
Change
Change in
Stake
FCM
1
Farallon Capital Management
California
$25.4M
KAM
2
Krensavage Asset Management
New York
$25.3M
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$23.3M +$11.4M +1,423,171 +272%
Vanguard Group
4
Vanguard Group
Pennsylvania
$23.2M -$302K -37,843 -2%
BlackRock
5
BlackRock
New York
$21.9M -$111K -13,925 -0.8%
Millennium Management
6
Millennium Management
New York
$11.3M -$4.08M -510,509 -35%
Acadian Asset Management
7
Acadian Asset Management
Massachusetts
$10.4M
CC
8
Commodore Capital
New York
$9.58M +$6.39M +800,000 New
Geode Capital Management
9
Geode Capital Management
Massachusetts
$5.9M +$59.1K +7,397 +2%
Renaissance Technologies
10
Renaissance Technologies
New York
$5.74M +$80.7K +10,100 +2%
State Street
11
State Street
Massachusetts
$5.65M +$13.8K +1,722 +0.4%
SCM
12
Stonepine Capital Management
Oregon
$3.65M -$2.39M -299,066 -50%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$3.59M +$2.4M +300,000 New
Morgan Stanley
14
Morgan Stanley
New York
$3.38M -$31.1K -3,895 -1%
Marshall Wace
15
Marshall Wace
United Kingdom
$3.3M -$4.65M -582,023 -68%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$3.24M -$60.5K -7,572 -3%
AQR Capital Management
17
AQR Capital Management
Connecticut
$2.72M -$1.35M -169,265 -43%
D.E. Shaw & Co
18
D.E. Shaw & Co
New York
$2.7M -$452K -56,532 -20%
Northern Trust
19
Northern Trust
Illinois
$2.34M -$442K -55,318 -22%
Jacobs Levy Equity Management
20
Jacobs Levy Equity Management
New Jersey
$2.02M -$184K -23,022 -12%
Charles Schwab
21
Charles Schwab
California
$1.99M +$15.2K +1,900 +1%
Goldman Sachs
22
Goldman Sachs
New York
$1.99M +$402K +50,298 +43%
N
23
Nuveen
North Carolina
$1.97M +$958K +119,875 +267%
TI
24
Trexquant Investment
Connecticut
$1.52M -$1.1M -137,595 -52%
TCM
25
Tang Capital Management
California
$1.52M

ENTA Hedge Fund Activity: Q3 2025 in Review

121 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Enanta Pharmaceuticals (ENTA) for Q3 2025, worth a combined $227M — up 63% from $139M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new ENTA positions and 11 closed out — a net gain of 14 holders — while 32 added to existing stakes and 43 trimmed.

The largest buyer was Janus Henderson Group, adding an estimated $11.4M. The largest seller was Marshall Wace, cutting an estimated $4.65M.

  • 121 institutional investors held Enanta Pharmaceuticals (ENTA) as of Q3 2025, up from 107 in Q2 2025.
  • Funds reported $227M of Enanta Pharmaceuticals stock for Q3 2025, up 63% quarter-over-quarter.
  • 25 funds opened new Enanta Pharmaceuticals positions in Q3 2025 and 11 closed out, a net change of +14 holders.
  • The largest Enanta Pharmaceuticals buyer in Q3 2025 was Janus Henderson Group, an estimated $11.4M added.
  • The largest Enanta Pharmaceuticals seller in Q3 2025 was Marshall Wace, an estimated $4.65M sold.

Based on aggregated 13F filings for Q3 2025.