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Enanta Pharmaceuticals

132 hedge funds and large institutions have $338M invested in Enanta Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 49 increasing their positions, 33 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

131% more call options, than puts

Call options by funds: $496K | Put options by funds: $215K

48% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 33

14% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 21

0.82% more ownership

Funds ownership: 91.43%92.26% (+0.82%)

1% more funds holding

Funds holding: 131132 (+1)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

19% less capital invested

Capital invested by funds: $416M → $338M (-$78M)

Holders
132
Holders Change
+1
Holders Change %
+0.76%
% of All Funds
1.62%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
49
Reduced
33
Closed
21
Calls
$496K
Puts
$215K
Net Calls
+$281K
Net Calls Change
-$1.78M
Name Holding Trade Value Shares
Change
Change in
Stake
PNC Financial Services Group
101
PNC Financial Services Group
Pennsylvania
$7.02K -$3.08K -230 -29%
Simplex Trading
102
Simplex Trading
Illinois
$5.75K -$6.26K -467 -51%
AF
103
Allworth Financial
California
$5.37K +$2.64K +197 +86%
IA
104
IFP Advisors
Florida
$5K
Fifth Third Bancorp
105
Fifth Third Bancorp
Ohio
$4.63K +$4.92K +367 New
RTL
106
Red Tortoise LLC
Georgia
$4.6K
Nisa Investment Advisors
107
Nisa Investment Advisors
Missouri
$4.29K
CMBA
108
C.M. Bidwell & Associates
Hawaii
$4.18K +$4.44K +331 New
RIL
109
Rothschild Investment LLC
Illinois
$3.84K +$684 +51 +20%
Optiver Holding
110
Optiver Holding
Netherlands
$3.26K
JFGIW
111
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$2.38K
FFA
112
Farther Finance Advisors
California
$2.28K +$94 +7 +4%
SAM
113
Smartleaf Asset Management
Massachusetts
$2.24K -$3.03K -226 -55%
MCM
114
MAI Capital Management
Ohio
$2.24K +$2.28K +170 +2,429%
RFP
115
Root Financial Partners
California
$1.49K +$1.58K +118 New
Los Angeles Capital Management
116
Los Angeles Capital Management
California
$1.3K
Group One Trading
117
Group One Trading
Illinois
$1.15K +$1.22K +91 New
AAP
118
Arax Advisory Partners
Colorado
$1.14K +$1.13K +84 +1,400%
Royal Bank of Canada
119
Royal Bank of Canada
Ontario, Canada
$1K -$10.3K -770 -88%
PFBT
120
Parkside Financial Bank & Trust
Missouri
$897
SS
121
Sunbelt Securities
Texas
$796
TM
122
Torren Management
California
$745 -$818 -61 -51%
PWA
123
Physician Wealth Advisors
Utah
$581 +$617 +46 New
KFAS
124
Keating Financial Advisory Services
Kansas
$88 +$94 +7 New
JWM
125
JPL Wealth Management
Colorado
$76 +$80 +6 New

ENTA Hedge Fund Activity: Q1 2026 in Review

132 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Enanta Pharmaceuticals (ENTA) for Q1 2026, worth a combined $338M — down 19% from $416M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new ENTA positions and 21 closed out — a net gain of 3 holders — while 49 added to existing stakes and 33 trimmed.

The largest buyer was Spruce Street Capital, adding an estimated $7.28M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $6.92M sold.

  • 132 institutional investors held Enanta Pharmaceuticals (ENTA) as of Q1 2026, up from 131 in Q4 2025.
  • Funds reported $338M of Enanta Pharmaceuticals stock for Q1 2026, down 19% quarter-over-quarter.
  • 24 funds opened new Enanta Pharmaceuticals positions in Q1 2026 and 21 closed out, a net change of +3 holders.
  • The largest Enanta Pharmaceuticals buyer in Q1 2026 was Spruce Street Capital, an estimated $7.28M added.
  • The largest Enanta Pharmaceuticals seller in Q1 2026 was Point72 Asset Management, an estimated $6.92M sold.

Based on aggregated 13F filings for Q1 2026.