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Enanta Pharmaceuticals

132 hedge funds and large institutions have $338M invested in Enanta Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 49 increasing their positions, 33 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

131% more call options, than puts

Call options by funds: $496K | Put options by funds: $215K

48% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 33

14% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 21

0.82% more ownership

Funds ownership: 91.43%92.26% (+0.82%)

1% more funds holding

Funds holding: 131132 (+1)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

19% less capital invested

Capital invested by funds: $416M → $338M (-$78M)

Holders
132
Holders Change
+1
Holders Change %
+0.76%
% of All Funds
1.62%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
49
Reduced
33
Closed
21
Calls
$496K
Puts
$215K
Net Calls
+$281K
Net Calls Change
-$1.78M
Name Holding Trade Value Shares
Change
Change in
Stake
XT
51
XTX Topco
Cayman Islands
$419K +$445K +33,211 New
RhumbLine Advisers
52
RhumbLine Advisers
Massachusetts
$397K +$34.2K +2,554 +9%
Thrivent Financial for Lutherans
53
Thrivent Financial for Lutherans
Minnesota
$359K
Fidelity Investments
54
Fidelity Investments
Massachusetts
$344K +$308K +22,960 +532%
Bank of America
55
Bank of America
North Carolina
$336K -$528K -39,385 -60%
PGA
56
Portland Global Advisors
Maine
$307K
VGA
57
Vanguard Global Advisers
Pennsylvania
$291K +$309K +23,054 New
HT
58
Headlands Technologies
Illinois
$286K +$295 +22 +0.1%
BCM
59
Bridgeway Capital Management
Texas
$280K -$101K -7,500 -25%
Carson Wealth (CWM LLC)
60
Carson Wealth (CWM LLC)
Nebraska
$277K +$17.1K +1,275 +6%
FRM
61
Fox Run Management
Connecticut
$250K +$138K +10,319 +101%
Deutsche Bank
62
Deutsche Bank
Germany
$245K -$63.2K -4,712 -20%
T. Rowe Price Associates
63
T. Rowe Price Associates
Maryland
$237K +$57.6K +4,294 +30%
State of Wisconsin Investment Board
64
State of Wisconsin Investment Board
Wisconsin
$235K
Barclays
65
Barclays
United Kingdom
$232K -$491K -36,595 -67%
EGM
66
Engineers Gate Manager
New York
$215K +$228K +17,013 New
BNP Paribas Financial Markets
67
BNP Paribas Financial Markets
France
$212K -$1.11M -83,075 -83%
MAM
68
Martingale Asset Management
Massachusetts
$209K +$222K +16,552 New
PAP
69
Persistent Asset Partners
Hong Kong
$209K -$12.6K -941 -5%
MIM
70
MetLife Investment Management
New Jersey
$196K +$15.2K +1,134 +8%
Susquehanna International Group
71
Susquehanna International Group
Pennsylvania
$179K +$50.1K +3,741 +36%
Wealth Enhancement Advisory Services
72
Wealth Enhancement Advisory Services
Minnesota
$179K +$38.8K +2,898 +27%
Squarepoint
73
Squarepoint
New York
$171K -$702K -52,399 -79%
SOW
74
State of Wyoming
Wyoming
$170K -$260K -19,414 -59%
Mirae Asset Global ETFs Holdings
75
Mirae Asset Global ETFs Holdings
Hong Kong
$164K +$4.1K +306 +2%

ENTA Hedge Fund Activity: Q1 2026 in Review

132 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Enanta Pharmaceuticals (ENTA) for Q1 2026, worth a combined $338M — down 19% from $416M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new ENTA positions and 21 closed out — a net gain of 3 holders — while 49 added to existing stakes and 33 trimmed.

The largest buyer was Spruce Street Capital, adding an estimated $7.28M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $6.92M sold.

  • 132 institutional investors held Enanta Pharmaceuticals (ENTA) as of Q1 2026, up from 131 in Q4 2025.
  • Funds reported $338M of Enanta Pharmaceuticals stock for Q1 2026, down 19% quarter-over-quarter.
  • 24 funds opened new Enanta Pharmaceuticals positions in Q1 2026 and 21 closed out, a net change of +3 holders.
  • The largest Enanta Pharmaceuticals buyer in Q1 2026 was Spruce Street Capital, an estimated $7.28M added.
  • The largest Enanta Pharmaceuticals seller in Q1 2026 was Point72 Asset Management, an estimated $6.92M sold.

Based on aggregated 13F filings for Q1 2026.