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Enliven Therapeutics

125 hedge funds and large institutions have $961M invested in Enliven Therapeutics in 2025 Q4 according to their latest regulatory filings, with 19 funds opening new positions, 46 increasing their positions, 45 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

4.85% more ownership

Funds ownership: 100.28%105.13% (+4.8%)

2% more repeat investments, than reductions

Existing positions increased: 46 | Existing positions reduced: 45

7% less funds holding

Funds holding: 134125 (-9)

21% less capital invested

Capital invested by funds: $1.22B → $961M (-$255M)

27% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 26

67% less funds holding in top 10

Funds holding in top 10: 62 (-4)

73% less call options, than puts

Call options by funds: $203K | Put options by funds: $765K

Holders
125
Holders Change
-9
Holders Change %
-6.72%
% of All Funds
1.52%
Holding in Top 10
2
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-66.67%
% of All Funds
0.02%
New
19
Increased
46
Reduced
45
Closed
26
Calls
$203K
Puts
$765K
Net Calls
-$562K
Net Calls Change
+$834K
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$123M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$109M -$430K -21,561 -0.3%
CC
3
Commodore Capital
New York
$72.3M
VPC
4
Vestal Point Capital
New York
$59M +$53.2M +2,670,000 +230%
FFM
5
Fairmount Funds Management
Pennsylvania
$57.2M
BlackRock
6
BlackRock
New York
$55.6M +$1.89M +94,802 +3%
PCH
7
Polar Capital Holdings
United Kingdom
$54.1M +$8.34M +418,673 +14%
VA
8
VR Adviser
New York
$49.7M
Vanguard Group
9
Vanguard Group
Pennsylvania
$43.1M +$4.95M +248,651 +10%
Janus Henderson Group
10
Janus Henderson Group
United Kingdom
$25.7M -$2.43M -121,859 -7%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$23.2M +$9.25M +464,191 +45%
NHAS
12
Novo Holdings A/S
Denmark
$22.8M +$1.07M +53,740 +4%
Citadel Advisors
13
Citadel Advisors
Florida
$21.9M +$5.26M +263,841 +23%
Capital Research Global Investors
14
Capital Research Global Investors
California
$20.1M -$222K -11,119 -0.8%
Pictet Asset Management
15
Pictet Asset Management
Switzerland
$20.1M -$1.89M -94,852 -7%
State Street
16
State Street
Massachusetts
$16.2M +$1.75M +87,725 +9%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$16.2M -$723K -36,291 -3%
SCM
18
Soleus Capital Management
Connecticut
$15.8M +$20.4M +1,025,000 New
Blackstone Inc
19
Blackstone Inc
New York
$14.7M -$7.28M -365,646 -28%
RSCM
20
Rock Springs Capital Management
Maryland
$12.3M +$2.24M +112,298 +16%
5VM
21
5AM Venture Management
California
$11.9M
CS
22
Candriam SCA
Luxembourg
$6.98M -$3.11M -156,333 -26%
SSC
23
Spruce Street Capital
New York
$6.87M +$8.89M +446,084 New
Morgan Stanley
24
Morgan Stanley
New York
$6.34M +$3.06M +153,439 +59%
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$6.14M +$4.75M +238,434 +149%