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Enliven Therapeutics

134 hedge funds and large institutions have $1.22B invested in Enliven Therapeutics in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 59 increasing their positions, 32 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more first-time investments, than exits

New positions opened: 20 | Existing positions closed: 10

84% more repeat investments, than reductions

Existing positions increased: 59 | Existing positions reduced: 32

8% more funds holding

Funds holding: 124134 (+10)

2% more capital invested

Capital invested by funds: $1.19B → $1.22B (+$23.4M)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

20.85% less ownership

Funds ownership: 121.12%100.28% (-21%)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1.4M

Holders
134
Holders Change
+10
Holders Change %
+8.06%
% of All Funds
1.76%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
20
Increased
59
Reduced
32
Closed
10
Calls
Puts
$1.4M
Net Calls
-$1.4M
Net Calls Change
-$1.38M
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$163M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$146M -$8.68M -430,705 -6%
CC
3
Commodore Capital
New York
$96.1M
FFM
4
Fairmount Funds Management
Pennsylvania
$76M
BlackRock
5
BlackRock
New York
$72M +$11.1M +551,390 +19%
VA
6
VR Adviser
New York
$66M -$16.1M -800,000 -20%
PCH
7
Polar Capital Holdings
United Kingdom
$63.4M +$901K +44,713 +1%
Vanguard Group
8
Vanguard Group
Pennsylvania
$52.3M +$2.87M +142,378 +6%
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$36.7M +$1.56M +77,171 +4%
NHAS
10
Novo Holdings A/S
Denmark
$29.2M +$6.89M +341,828 +32%
Pictet Asset Management
11
Pictet Asset Management
Switzerland
$28.6M +$8.68M +430,585 +45%
Blackstone Inc
12
Blackstone Inc
New York
$27M
Capital Research Global Investors
13
Capital Research Global Investors
California
$26.9M
Citadel Advisors
14
Citadel Advisors
Florida
$23.8M -$6.25M -309,921 -21%
VPC
15
Vestal Point Capital
New York
$23.7M +$18.3M +910,000 +364%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$22.2M +$4.08M +202,260 +23%
Point72 Asset Management
17
Point72 Asset Management
Connecticut
$21.3M -$6.3M -312,668 -23%
State Street
18
State Street
Massachusetts
$19.8M +$3M +148,895 +18%
DFO
19
Duquesne Family Office
New York
$19.4M +$9.76M +484,405 +105%
FTM
20
First Turn Management
California
$16M +$5.51M +273,424 +54%
5VM
21
5AM Venture Management
California
$15.8M
RSCM
22
Rock Springs Capital Management
Maryland
$14M -$308K -15,301 -2%
CS
23
Candriam SCA
Luxembourg
$12.5M +$3.88M +192,702 +46%
Franklin Resources
24
Franklin Resources
California
$8.81M
AAA
25
Affinity Asset Advisors
New York
$8.19M

ELVN Hedge Fund Activity: Q3 2025 in Review

134 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Enliven Therapeutics (ELVN) for Q3 2025, worth a combined $1.22B — up 2% from $1.19B a quarter earlier.

Buyers outnumbered sellers: 20 funds opened new ELVN positions and 10 closed out — a net gain of 10 holders — while 59 added to existing stakes and 32 trimmed.

The largest buyer was Vestal Point Capital, adding an estimated $18.3M. The largest seller was RA Capital Management, exiting entirely with an estimated $17M sold.

  • 134 institutional investors held Enliven Therapeutics (ELVN) as of Q3 2025, up from 124 in Q2 2025.
  • Funds reported $1.22B of Enliven Therapeutics stock for Q3 2025, up 2% quarter-over-quarter.
  • 20 funds opened new Enliven Therapeutics positions in Q3 2025 and 10 closed out, a net change of +10 holders.
  • The largest Enliven Therapeutics buyer in Q3 2025 was Vestal Point Capital, an estimated $18.3M added.
  • The largest Enliven Therapeutics seller in Q3 2025 was RA Capital Management, an estimated $17M sold.

Based on aggregated 13F filings for Q3 2025.