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Enliven Therapeutics

124 hedge funds and large institutions have $1.19B invested in Enliven Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 57 increasing their positions, 23 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more repeat investments, than reductions

Existing positions increased: 57 | Existing positions reduced: 23

21% more capital invested

Capital invested by funds: $984M → $1.19B (+$208M)

20% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 20

19.31% more ownership

Funds ownership: 101.81%121.12% (+19%)

2% more funds holding

Funds holding: 121124 (+3)

0% more funds holding in top 10

Funds holding in top 10: 77 (0)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $14K

Holders
124
Holders Change
+3
Holders Change %
+2.48%
% of All Funds
1.63%
Holding in Top 10
7
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.09%
New
24
Increased
57
Reduced
23
Closed
20
Calls
Puts
$14K
Net Calls
-$14K
Net Calls Change
+$3K
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$160M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$152M +$18M +950,372 +14%
CC
3
Commodore Capital
New York
$94.1M +$337K +17,809 +0.4%
VA
4
VR Adviser
New York
$80.8M
FFM
5
Fairmount Funds Management
Pennsylvania
$74.5M +$9.63M +508,646 +16%
PCH
6
Polar Capital Holdings
United Kingdom
$61.2M +$13M +685,000 +29%
BlackRock
7
BlackRock
New York
$59.5M -$587K -30,995 -1%
Vanguard Group
8
Vanguard Group
Pennsylvania
$48.4M +$8.3M +438,397 +22%
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$34.4M +$2.76M +145,909 +9%
Citadel Advisors
10
Citadel Advisors
Florida
$29.5M +$6.57M +347,286 +31%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$27.1M +$23M +1,213,160 +867%
Blackstone Inc
12
Blackstone Inc
New York
$26.5M +$10.6M +558,285 +73%
Capital Research Global Investors
13
Capital Research Global Investors
California
$26.4M +$24.9M +1,315,465 New
WP
14
Woodline Partners
California
$22.1M +$5.59M +295,500 +37%
NHAS
15
Novo Holdings A/S
Denmark
$21.8M +$20.5M +1,084,432 New
Pictet Asset Management
16
Pictet Asset Management
Switzerland
$19.4M
Geode Capital Management
17
Geode Capital Management
Massachusetts
$17.7M +$1.2M +63,580 +8%
RCM
18
RA Capital Management
Massachusetts
$17M
State Street
19
State Street
Massachusetts
$16.4M +$669K +35,340 +5%
5VM
20
5AM Venture Management
California
$15.5M -$10.4M -550,000 -42%
RSCM
21
Rock Springs Capital Management
Maryland
$14.1M +$4.46M +235,537 +51%
T. Rowe Price Associates
22
T. Rowe Price Associates
Maryland
$10.6M +$9.69M +512,090 +3,169%
FTM
23
First Turn Management
California
$10.2M -$475K -25,105 -5%
TCM
24
TCG Crossover Management
California
$9.99M +$9.43M +498,000 New
DFO
25
Duquesne Family Office
New York
$9.29M +$8.77M +463,000 New

ELVN Hedge Fund Activity: Q2 2025 in Review

124 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Enliven Therapeutics (ELVN) for Q2 2025, worth a combined $1.19B — up 21% from $984M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new ELVN positions and 20 closed out — a net gain of 4 holders — while 57 added to existing stakes and 23 trimmed.

The largest buyer was Capital Research Global Investors, opening a new position worth an estimated $24.9M. The largest seller was Boxer Capital Management, exiting entirely with an estimated $13.2M sold.

  • 124 institutional investors held Enliven Therapeutics (ELVN) as of Q2 2025, up from 121 in Q1 2025.
  • Funds reported $1.19B of Enliven Therapeutics stock for Q2 2025, up 21% quarter-over-quarter.
  • 24 funds opened new Enliven Therapeutics positions in Q2 2025 and 20 closed out, a net change of +4 holders.
  • The largest Enliven Therapeutics buyer in Q2 2025 was Capital Research Global Investors, an estimated $24.9M added.
  • The largest Enliven Therapeutics seller in Q2 2025 was Boxer Capital Management, an estimated $13.2M sold.

Based on aggregated 13F filings for Q2 2025.