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Enliven Therapeutics

121 hedge funds and large institutions have $984M invested in Enliven Therapeutics in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 43 increasing their positions, 35 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

62% more first-time investments, than exits

New positions opened: 21 | Existing positions closed: 13

23% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 35

7% more funds holding

Funds holding: 113121 (+8)

0.24% more ownership

Funds ownership: 101.57%101.81% (+0.24%)

12% less capital invested

Capital invested by funds: $1.12B → $984M (-$133M)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

81% less call options, than puts

Call options by funds: $4K | Put options by funds: $21K

Holders
121
Holders Change
+8
Holders Change %
+7.08%
% of All Funds
1.62%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
21
Increased
43
Reduced
35
Closed
13
Calls
$4K
Puts
$21K
Net Calls
-$17K
Net Calls Change
-$35K
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$157M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$130M +$2.45M +113,658 +2%
CC
3
Commodore Capital
New York
$92M +$10.1M +470,000 +11%
VA
4
VR Adviser
New York
$79.2M
FFM
5
Fairmount Funds Management
Pennsylvania
$63M
BlackRock
6
BlackRock
New York
$59M +$710K +33,001 +1%
PCH
7
Polar Capital Holdings
United Kingdom
$46.5M -$525K -24,374 -1%
Vanguard Group
8
Vanguard Group
Pennsylvania
$38.8M -$73.5K -3,416 -0.2%
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$33.1M +$5.14M +238,626 +18%
5VM
10
5AM Venture Management
California
$26M -$6.61M -307,288 -19%
Citadel Advisors
11
Citadel Advisors
Florida
$22.1M -$13.2M -615,394 -35%
Pictet Asset Management
12
Pictet Asset Management
Switzerland
$19M -$103K -4,791 -0.5%
RCM
13
RA Capital Management
Massachusetts
$16.7M
Geode Capital Management
14
Geode Capital Management
Massachusetts
$16.1M +$1.21M +56,455 +7%
WP
15
Woodline Partners
California
$15.8M -$16.5K -765 -0.1%
State Street
16
State Street
Massachusetts
$15.4M -$450K -20,930 -3%
Blackstone Inc
17
Blackstone Inc
New York
$15M +$8.37M +388,984 +104%
BCM
18
Boxer Capital Management
California
$13.2M
FTM
19
First Turn Management
California
$10.5M
RSCM
20
Rock Springs Capital Management
Maryland
$9.17M +$803K +37,300 +9%
Adage Capital Partners
21
Adage Capital Partners
Massachusetts
$8.86M -$4.3M -200,000 -31%
Northern Trust
22
Northern Trust
Illinois
$6.66M +$154K +7,150 +2%
IC
23
Ikarian Capital
Texas
$5.7M -$2.26M -105,000 -27%
ACP
24
Acuta Capital Partners
California
$5.22M -$45.2K -2,099 -0.8%
Charles Schwab
25
Charles Schwab
California
$5.11M -$50.6K -2,351 -0.9%

ELVN Hedge Fund Activity: Q1 2025 in Review

121 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Enliven Therapeutics (ELVN) for Q1 2025, worth a combined $984M — down 12% from $1.12B a quarter earlier.

Buyers outnumbered sellers: 21 funds opened new ELVN positions and 13 closed out — a net gain of 8 holders — while 43 added to existing stakes and 35 trimmed.

The largest buyer was Commodore Capital, adding an estimated $10.1M. The largest seller was Citadel Advisors, cutting an estimated $13.2M.

  • 121 institutional investors held Enliven Therapeutics (ELVN) as of Q1 2025, up from 113 in Q4 2024.
  • Funds reported $984M of Enliven Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 21 funds opened new Enliven Therapeutics positions in Q1 2025 and 13 closed out, a net change of +8 holders.
  • The largest Enliven Therapeutics buyer in Q1 2025 was Commodore Capital, an estimated $10.1M added.
  • The largest Enliven Therapeutics seller in Q1 2025 was Citadel Advisors, an estimated $13.2M sold.

Based on aggregated 13F filings for Q1 2025.