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Dyne Therapeutics
DYN

227 hedge funds and large institutions have $3.4B invested in Dyne Therapeutics in 2026 Q1 according to their latest regulatory filings, with 42 funds opening new positions, 100 increasing their positions, 60 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 60

2% less capital invested

Capital invested by funds: $3.48B → $3.4B (-$78.1M)

7% less first-time investments, than exits

New positions opened: 42 | Existing positions closed: 45

2% less funds holding

Funds holding: 232 → 227 (-5)

10.74% less ownership

Funds ownership: 124.57% → 113.83% (-11%)

29% less funds holding in top 10

Funds holding in top 10: 7 → 5 (-2)

83% less call options, than puts

Call options by funds: $769K | Put options by funds: $4.47M

Holders
227
Holders Change
-5
Holders Change %
-2.16%
% of All Funds
2.79%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.06%
New
42
Increased
100
Reduced
60
Closed
45
Calls
$769K
Puts
$4.47M
Net Calls
-$3.7M
Net Calls Change
-$596K

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$228M
2
VPC
Vestal Point Capital
New York
+$66.9M
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$40.3M
4
OAG
Orbis Allan Gray
Bermuda
+$33.8M
5
Fiera Capital (Canada)
Fiera Capital (Canada)
Quebec, Canada
+$23.8M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$71.9M
2
SL
Siren LLC
Connecticut
-$22M
3
CS
Candriam SCA
Luxembourg
-$20.7M
4
VC
Vivo Capital
California
-$18.2M
5
Citadel Advisors
Citadel Advisors
Florida
-$16.7M
Name Holding Trade Value Shares
Change 		Change in
Stake
CIBC World Market
101
CIBC World Market
Ontario, Canada
$1.25M +$7.74K +449 +0.7%
State of Wisconsin Investment Board
102
State of Wisconsin Investment Board
Wisconsin
$1.24M +$84.8K +4,918 +8%
Envestnet Asset Management
103
Envestnet Asset Management
Illinois
$1.24M +$1.18M +68,393 New
Royal Bank of Canada
104
Royal Bank of Canada
Ontario, Canada
$1.24M +$856K +49,641 +268%
YIH
105
Y-Intercept (HK)
Hong Kong
$1.18M -$4.8M -278,568 -81%
Manulife (Manufacturers Life Insurance)
106
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.16M -$63.1K -3,657 -5%
DekaBank Deutsche Girozentrale
107
DekaBank Deutsche Girozentrale
Germany
$1.09M – – –
Blackstone Inc
108
Blackstone Inc
New York
$1.04M +$985K +57,107 New
VGA
109
Vanguard Global Advisers
Pennsylvania
$1.02M +$972K +56,392 New
Fifth Third Bancorp
110
Fifth Third Bancorp
Ohio
$983K +$935K +54,229 New
Victory Capital Management
111
Victory Capital Management
Texas
$961K +$25.8K +1,496 +3%
Zurich Cantonal Bank
112
Zurich Cantonal Bank
Switzerland
$946K +$899K +52,152 New
AIM
113
Arcadia Investment Management
Michigan
$897K +$27.6K +1,600 +3%
Wellington Management Group
114
Wellington Management Group
Massachusetts
$886K +$30.8K +1,786 +4%
MP
115
Mangrove Partners
Connecticut
$869K +$826K +47,927 New
ACM
116
ADAR1 Capital Management
Texas
$861K +$82.6K +4,789 +11%
SEI Investments
117
SEI Investments
Pennsylvania
$815K -$238K -13,782 -23%
XT
118
XTX Topco
Cayman Islands
$774K -$241K -13,951 -25%
Russell Investments Group
119
Russell Investments Group
United Kingdom
$726K -$3.31M -191,977 -83%
State of New Jersey Common Pension Fund D
120
State of New Jersey Common Pension Fund D
New Jersey
$714K +$135K +7,828 +25%
BNP Paribas Financial Markets
121
BNP Paribas Financial Markets
France
$711K +$254K +14,727 +60%
Citigroup
122
Citigroup
New York
$685K +$19.7K +1,140 +3%
BHCM
123
Brevan Howard Capital Management
Jersey
$675K -$2.08M -120,755 -76%
Barclays
124
Barclays
United Kingdom
$663K -$7.11M -412,089 -92%
PFSRSONJ
125
Police & Firemen's Retirement System of New Jersey
New Jersey
$658K +$47.5K +2,757 +8%
3 4
5
6 7

DYN Hedge Fund Activity: Q1 2026 in Review

227 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Dyne Therapeutics (DYN) for Q1 2026, worth a combined $3.4B — down 2.2% from $3.48B a quarter earlier.

Sellers outnumbered buyers: 45 funds closed out of DYN and 42 opened new positions — a net loss of 3 holders — while 60 trimmed existing stakes and 100 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $228M. The largest seller was Adage Capital Partners, cutting an estimated $71.9M.

  • 227 institutional investors held Dyne Therapeutics (DYN) as of Q1 2026, down from 232 in Q4 2025.
  • Funds reported $3.4B of Dyne Therapeutics stock for Q1 2026, down 2.2% quarter-over-quarter.
  • 42 funds opened new Dyne Therapeutics positions in Q1 2026 and 45 closed out, a net change of -3 holders.
  • The largest Dyne Therapeutics buyer in Q1 2026 was T. Rowe Price Investment Management, an estimated $228M added.
  • The largest Dyne Therapeutics seller in Q1 2026 was Adage Capital Partners, an estimated $71.9M sold.

Based on aggregated 13F filings for Q1 2026.