DFTX

Definium Therapeutics

194 hedge funds and large institutions have $469M invested in Definium Therapeutics in 2025 Q3 according to their latest regulatory filings, with 39 funds opening new positions, 56 increasing their positions, 48 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
194
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$21.3M
Puts
$10.9M
Net Calls
Net Calls Change

Top Buyers

1 +$4.18M
2 +$3.43M
3 +$3.08M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$2.8M
5
Two Sigma Investments
Two Sigma Investments
New York
+$2.24M

Top Sellers

1 -$16.6M
2 -$9.69M
3 -$9.33M
4
Blackstone Inc
Blackstone Inc
New York
-$7.56M
5
ABG
Ally Bridge Group
New York
-$3.4M
Name Holding Trade Value Shares
Change
Change in
Stake
BNP Paribas Asset Management
151
BNP Paribas Asset Management
France
$9K
ASN
152
Advisory Services Network
Georgia
$7.74K
Walleye Trading
153
Walleye Trading
New York
$6.63K
HI
154
Harbour Investments
Wisconsin
$6.55K
GRP
155
Global Retirement Partners
California
$5.89K
FFA
156
Farther Finance Advisors
California
$5.39K
MPWT
157
MassMutual Private Wealth & Trust
Connecticut
$5.09K
NL
158
NVWM LLC
Pennsylvania
$4.91K
TIM
159
Tortoise Investment Management
New York
$4.72K
Rockefeller Capital Management
160
Rockefeller Capital Management
New York
$4.14K
RIL
161
Rothschild Investment LLC
Illinois
$3.22K
Daiwa Securities Group
162
Daiwa Securities Group
Japan
$3K
PA
163
Parallel Advisors
California
$2.74K
Optiver Holding
164
Optiver Holding
Netherlands
$2.57K
AEPWM
165
Atlantic Edge Private Wealth Management
Florida
$2.28K
Northwestern Mutual Wealth Management
166
Northwestern Mutual Wealth Management
Wisconsin
$1.96K
CIBC Private Wealth Group
167
CIBC Private Wealth Group
Georgia
$1.78K
NA
168
NewEdge Advisors
Louisiana
$1.67K
SS
169
SBI Securities
Japan
$1.24K
EWA
170
EverSource Wealth Advisors
Alabama
$1.23K
NS
171
NBC Securities
Alabama
$1.18K
HWM
172
HighMark Wealth Management
Minnesota
$1.18K
AF
173
Allworth Financial
California
$1K
AWM
174
Activest Wealth Management
Florida
$778
GA
175
Guerra Advisors
Florida
$778