|
1
|
EcoR1 Capital
San Francisco,
California
|
$9.9M
|
–
|
–
|
–
|
|
|
2
|
Jennison Associates
New York
|
$8.18M
|
–
|
–
|
–
|
|
|
3
|
Ameriprise
Minneapolis,
Minnesota
|
$7.66M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$7.48M
|
–
|
–
|
–
|
|
|
5
|
Primecap Management
Pasadena,
California
|
$5.47M
|
–
|
–
|
–
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$4.49M
|
–
|
–
|
–
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$4.45M
|
-$10.5M
|
-1
|
Closed
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$4.43M
|
–
|
–
|
–
|
|
|
9
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$3.13M
|
–
|
–
|
–
|
|
|
10
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.9M
|
–
|
–
|
–
|
|
|
11
|
|
$2.81M
|
–
|
–
|
–
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.8M
|
–
|
–
|
–
|
|
|
13
|
Lazard Asset Management
New York
|
$2.07M
|
–
|
–
|
–
|
|
|
14
|
C WorldWide Group
Copenhagen,
Denmark
|
$1.87M
|
–
|
–
|
–
|
|
|
15
|
Pura Vida Investments
New York
|
$1.77M
|
–
|
–
|
–
|
|
|
16
|
Principal Financial Group
Des Moines,
Iowa
|
$1.56M
|
–
|
–
|
–
|
|
|
17
|
Lombard Odier Asset Management (USA)
New York
|
$1.42M
|
–
|
–
|
–
|
|
|
18
|
Acuta Capital Partners
Redwood City,
California
|
$1.1M
|
–
|
–
|
–
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$861K
|
–
|
–
|
–
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$807K
|
–
|
–
|
–
|
|
|
21
|
BlackRock Institutional Trust
San Francisco,
California
|
$781K
|
–
|
–
|
–
|
|
|
22
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$710K
|
–
|
–
|
–
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$638K
|
–
|
–
|
–
|
|
|
24
|
Spark Investment Management
New York
|
$592K
|
–
|
–
|
–
|
|
|
25
|
|
$562K
|
–
|
–
|
–
|
|
