|
1
|
EcoR1 Capital
San Francisco,
California
|
$15.6M
|
–
|
–
|
–
|
|
|
2
|
Jennison Associates
New York
|
$12.4M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$10.5M
|
–
|
–
|
–
|
|
|
4
|
Ameriprise
Minneapolis,
Minnesota
|
$8.11M
|
–
|
–
|
–
|
|
|
5
|
Capital World Investors
Los Angeles,
California
|
$5.9M
|
–
|
–
|
–
|
|
|
6
|
Primecap Management
Pasadena,
California
|
$5.61M
|
–
|
–
|
–
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$5.16M
|
–
|
–
|
–
|
|
|
8
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$4.35M
|
–
|
–
|
–
|
|
|
9
|
Tekla Capital Management
Boston,
Massachusetts
|
$4M
|
–
|
–
|
–
|
|
|
10
|
Lazard Asset Management
New York
|
$3.11M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.77M
|
–
|
–
|
–
|
|
|
12
|
BlackRock Fund Advisors
San Francisco,
California
|
$2.53M
|
–
|
–
|
–
|
|
|
13
|
|
$2.26M
|
–
|
–
|
–
|
|
|
14
|
Visium Asset Management
New York
|
$2.06M
|
–
|
–
|
–
|
|
|
15
|
Lombard Odier Asset Management (USA)
New York
|
$1.78M
|
–
|
–
|
–
|
|
|
16
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.74M
|
–
|
–
|
–
|
|
|
17
|
Acuta Capital Partners
Redwood City,
California
|
$1.53M
|
–
|
–
|
–
|
|
|
18
|
Principal Financial Group
Des Moines,
Iowa
|
$1.27M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$1.06M
|
–
|
–
|
–
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$971K
|
–
|
–
|
–
|
|
|
21
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$799K
|
–
|
–
|
–
|
|
|
22
|
Wall Street Associates
Lajolla,
California
|
$688K
|
–
|
–
|
–
|
|
|
23
|
State Street
Boston,
Massachusetts
|
$661K
|
–
|
–
|
–
|
|
|
24
|
BlackRock Institutional Trust
San Francisco,
California
|
$606K
|
–
|
–
|
–
|
|
|
25
|
Bank of New York Mellon
New York
|
$576K
|
–
|
–
|
–
|
|
