|
1
|
EcoR1 Capital
San Francisco,
California
|
$11.2M
|
–
|
–
|
–
|
|
|
2
|
Jennison Associates
New York
|
$7.89M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$7.36M
|
–
|
–
|
–
|
|
|
4
|
Ameriprise
Minneapolis,
Minnesota
|
$7.24M
|
–
|
–
|
–
|
|
|
5
|
Capital World Investors
Los Angeles,
California
|
$6.22M
|
+$13M
|
+1
|
New
|
|
|
6
|
Primecap Management
Pasadena,
California
|
$4.44M
|
–
|
–
|
–
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$4.28M
|
–
|
–
|
–
|
|
|
8
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$3.04M
|
–
|
–
|
–
|
|
|
9
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.79M
|
–
|
–
|
–
|
|
|
10
|
Lazard Asset Management
New York
|
$2.17M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.13M
|
–
|
–
|
–
|
|
|
12
|
BlackRock Fund Advisors
San Francisco,
California
|
$1.75M
|
–
|
–
|
–
|
|
|
13
|
|
$1.64M
|
–
|
–
|
–
|
|
|
14
|
Lombard Odier Asset Management (USA)
New York
|
$1.31M
|
–
|
–
|
–
|
|
|
15
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.22M
|
–
|
–
|
–
|
|
|
16
|
Acuta Capital Partners
Redwood City,
California
|
$1.06M
|
–
|
–
|
–
|
|
|
17
|
Principal Financial Group
Des Moines,
Iowa
|
$884K
|
–
|
–
|
–
|
|
|
18
|
Pura Vida Investments
New York
|
$865K
|
–
|
–
|
–
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$809K
|
–
|
–
|
–
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$771K
|
–
|
–
|
–
|
|
|
21
|
C WorldWide Group
Copenhagen,
Denmark
|
$756K
|
–
|
–
|
–
|
|
|
22
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$680K
|
–
|
–
|
–
|
|
|
23
|
BlackRock Institutional Trust
San Francisco,
California
|
$489K
|
–
|
–
|
–
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$459K
|
–
|
–
|
–
|
|
|
25
|
Bank of New York Mellon
New York
|
$421K
|
–
|
–
|
–
|
|
