|
1
|
EcoR1 Capital
San Francisco,
California
|
$15.8M
|
+$15.5M
|
+1
|
New
|
|
|
2
|
Jennison Associates
New York
|
$14.6M
|
+$15.5M
|
+1
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$12M
|
+$15.5M
|
+1
|
New
|
|
|
4
|
Ameriprise
Minneapolis,
Minnesota
|
$9.44M
|
+$15.5M
|
+1
|
New
|
|
|
5
|
Capital World Investors
Los Angeles,
California
|
$6.73M
|
–
|
–
|
–
|
|
|
6
|
Primecap Management
Pasadena,
California
|
$6.28M
|
–
|
–
|
–
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$5.88M
|
–
|
–
|
–
|
|
|
8
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$5.04M
|
–
|
–
|
–
|
|
|
9
|
Tekla Capital Management
Boston,
Massachusetts
|
$4.56M
|
–
|
–
|
–
|
|
|
10
|
Lazard Asset Management
New York
|
$3.54M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.97M
|
–
|
–
|
–
|
|
|
12
|
Visium Asset Management
New York
|
$2.94M
|
–
|
–
|
–
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$2.9M
|
–
|
–
|
–
|
|
|
14
|
|
$2.83M
|
–
|
–
|
–
|
|
|
15
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.96M
|
–
|
–
|
–
|
|
|
16
|
Lombard Odier Asset Management (USA)
New York
|
$1.84M
|
–
|
–
|
–
|
|
|
17
|
Acuta Capital Partners
Redwood City,
California
|
$1.76M
|
–
|
–
|
–
|
|
|
18
|
Principal Financial Group
Des Moines,
Iowa
|
$1.37M
|
–
|
–
|
–
|
|
|
19
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$1.2M
|
–
|
–
|
–
|
|
|
20
|
BlackRock Institutional Trust
San Francisco,
California
|
$818K
|
–
|
–
|
–
|
|
|
21
|
Wall Street Associates
Lajolla,
California
|
$784K
|
–
|
–
|
–
|
|
|
22
|
Soros Fund Management
New York
|
$588K
|
–
|
–
|
–
|
|
|
23
|
|
$586K
|
–
|
–
|
–
|
|
|
24
|
Bank of New York Mellon
New York
|
$557K
|
–
|
–
|
–
|
|
|
25
|
AWM Investment Company
New York
|
$490K
|
–
|
–
|
–
|
|
