|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$73.7M
|
-$16.2M
|
-2,357,749
|
-17%
|
|
|
2
|
|
$63.9M
|
+$21.1M
|
+3,072,502
|
+45%
|
|
|
3
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$41.8M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$40.1M
|
+$1.6M
|
+233,252
|
+4%
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$26.6M
|
+$545K
|
+79,255
|
+2%
|
|
|
6
|
Deerfield Management
New York
|
$24.2M
|
+$5.24M
|
+762,391
|
+26%
|
|
|
7
|
Pictet Asset Management
Carouge,
Switzerland
|
$24.2M
|
+$600K
|
+87,152
|
+2%
|
|
|
8
|
Alyeska Investment Group
Chicago,
Illinois
|
$19.6M
|
-$7.21M
|
-1,047,577
|
-26%
|
|
|
9
|
Vestal Point Capital
New York
|
$19.5M
|
+$2.76M
|
+401,873
|
+15%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$17.5M
|
-$117K
|
-17,013
|
-0.6%
|
|
|
11
|
Braidwell
Stamford,
Connecticut
|
$14.2M
|
-$9.32M
|
-1,355,255
|
-38%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$13.7M
|
-$1.66M
|
-240,823
|
-10%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$11.1M
|
+$1.18M
|
+171,964
|
+11%
|
|
|
14
|
|
$11M
|
+$835K
|
+121,368
|
+8%
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$9.21M
|
+$781K
|
+113,588
|
+9%
|
|
|
16
|
|
$8.8M
|
+$4.43M
|
+643,733
|
+91%
|
|
|
17
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$8.43M
|
+$1.01M
|
+146,300
|
+13%
|
|
|
18
|
Millennium Management
New York
|
$7.85M
|
-$772K
|
-112,293
|
-9%
|
|
|
19
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$7.29M
|
-$361K
|
-52,463
|
-4%
|
|
|
20
|
Renaissance Technologies
New York
|
$6.5M
|
+$4.49M
|
+652,100
|
+187%
|
|
|
21
|
Bank of America
Charlotte,
North Carolina
|
$6.28M
|
-$559K
|
-81,333
|
-8%
|
|
|
22
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$6.14M
|
+$4.56M
|
+663,418
|
+236%
|
|
|
23
|
Algert Global
San Francisco,
California
|
$5.89M
|
+$3.68M
|
+534,662
|
+144%
|
|
|
24
|
DAFNA Capital Management
Los Angeles,
California
|
$5.71M
|
+$1.02M
|
+147,800
|
+20%
|
|
|
25
|
EcoR1 Capital
San Francisco,
California
|
$5.6M
|
–
|
–
|
–
|
|
