|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$176M
|
+$41.8M
|
+1,964,917
|
+29%
|
|
|
2
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$164M
|
-$17M
|
-799,134
|
-9%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$141M
|
–
|
–
|
–
|
|
|
4
|
Canaan Partners XI
Menlo Park,
California
|
$139M
|
-$57.4M
|
-2,699,344
|
-28%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$60.9M
|
+$6.24M
|
+293,175
|
+11%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$52.4M
|
-$235K
|
-11,033
|
-0.4%
|
|
|
7
|
|
$50.9M
|
+$12.3M
|
+578,511
|
+29%
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$49.6M
|
+$241K
|
+11,326
|
+0.5%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$42M
|
+$1.14M
|
+53,569
|
+3%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$40.9M
|
+$35.8M
|
+1,682,955
|
+469%
|
|
|
11
|
|
$34.6M
|
-$3.6M
|
-169,395
|
-9%
|
|
|
12
|
Viking Global Investors
Stamford,
Connecticut
|
$31.2M
|
-$6.36M
|
-298,861
|
-16%
|
|
|
13
|
Polar Capital Holdings
London,
United Kingdom
|
$24.7M
|
+$5.61M
|
+263,879
|
+27%
|
|
|
14
|
Boxer Capital
San Diego,
California
|
$23.8M
|
–
|
–
|
–
|
|
|
15
|
Deerfield Management
New York
|
$20.7M
|
-$52.7M
|
-2,480,123
|
-71%
|
|
|
16
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$15.2M
|
+$16.1M
|
+757,407
|
New
|
|
|
17
|
Commodore Capital
New York
|
$14.8M
|
–
|
–
|
–
|
|
|
18
|
|
$11.4M
|
+$9.12M
|
+428,830
|
+310%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$11.1M
|
+$2.39M
|
+112,271
|
+25%
|
|
|
20
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$10.1M
|
+$10.7M
|
+504,251
|
New
|
|
|
21
|
Driehaus Capital Management
Chicago,
Illinois
|
$9.81M
|
-$249K
|
-11,717
|
-2%
|
|
|
22
|
Pathway Capital Management
Irvine,
California
|
$8.07M
|
+$8.57M
|
+403,127
|
New
|
|
|
23
|
Tang Capital Management
San Diego,
California
|
$8.01M
|
+$8.51M
|
+400,000
|
New
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$4.51M
|
+$735K
|
+34,540
|
+18%
|
|
|
25
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
$4.25M
|
+$2.07M
|
+97,441
|
+85%
|
|
