|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$115M
|
-$8.4M
|
-430,128
|
-5%
|
|
|
2
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$102M
|
+$783K
|
+40,077
|
+0.5%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$94.1M
|
–
|
–
|
–
|
|
|
4
|
Franklin Resources
San Mateo,
California
|
$45.5M
|
+$18.2M
|
+934,022
|
+38%
|
|
|
5
|
Braidwell
Stamford,
Connecticut
|
$42.2M
|
+$37.4M
|
+1,913,356
|
+153%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$41.9M
|
+$449K
|
+23,008
|
+0.7%
|
|
|
7
|
Canaan Partners XI
Menlo Park,
California
|
$34.1M
|
–
|
–
|
–
|
|
|
8
|
|
$30.5M
|
+$10.1M
|
+515,234
|
+29%
|
|
|
9
|
|
$30.2M
|
-$3.45M
|
-176,773
|
-7%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$30.2M
|
-$3.9M
|
-199,744
|
-8%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$22.3M
|
-$10.1M
|
-517,827
|
-24%
|
|
|
12
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$21.4M
|
+$16M
|
+816,836
|
+104%
|
|
|
13
|
Viking Global Investors
Stamford,
Connecticut
|
$20.8M
|
–
|
–
|
–
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$18.7M
|
–
|
–
|
–
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$15.9M
|
–
|
–
|
–
|
|
|
16
|
Adage Capital Partners
Boston,
Massachusetts
|
$9.89M
|
-$50M
|
-2,560,000
|
-78%
|
|
|
17
|
Commodore Capital
New York
|
$9.89M
|
–
|
–
|
–
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$7.87M
|
+$156K
|
+7,992
|
+1%
|
|
|
19
|
Janus Henderson Group
London,
|
$7.53M
|
+$11M
|
+562,794
|
New
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$6.67M
|
+$1.52M
|
+77,664
|
+18%
|
|
|
21
|
Driehaus Capital Management
Chicago,
Illinois
|
$6.31M
|
-$227K
|
-11,600
|
-2%
|
|
|
22
|
|
$5.67M
|
-$3.46M
|
-176,943
|
-29%
|
|
|
23
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$5.38M
|
-$2.03M
|
-103,738
|
-20%
|
|
|
24
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
$5.35M
|
+$3.43M
|
+175,737
|
+78%
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$5.27M
|
+$7.56M
|
+387,213
|
+5,635%
|
|
