|
1
|
RA Capital Management
Boston,
Massachusetts
|
$95.8M
|
–
|
–
|
–
|
|
|
2
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$93.4M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$73.9M
|
-$20M
|
-1,533,775
|
-20%
|
|
|
4
|
|
$57.5M
|
+$14.7M
|
+1,123,701
|
+32%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$56.8M
|
+$4.51M
|
+346,090
|
+8%
|
|
|
6
|
Franklin Resources
San Mateo,
California
|
$49.9M
|
+$21.7K
|
+1,664
|
+0%
|
|
|
7
|
Braidwell
Stamford,
Connecticut
|
$45.6M
|
+$4.61M
|
+353,760
|
+11%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$36M
|
-$5.46M
|
-418,407
|
-12%
|
|
|
9
|
Viking Global Investors
Stamford,
Connecticut
|
$31.4M
|
–
|
–
|
–
|
|
|
10
|
Canaan Partners XI
Menlo Park,
California
|
$30.6M
|
-$741K
|
-56,842
|
-2%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$28.3M
|
-$22.2K
|
-1,703
|
-0.1%
|
|
|
12
|
PFM Health Sciences
San Francisco,
California
|
$27.3M
|
+$14.1M
|
+1,077,458
|
+94%
|
|
|
13
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$26.9M
|
-$632K
|
-48,457
|
-2%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$23.7M
|
+$2.09M
|
+160,385
|
+9%
|
|
|
15
|
|
$20.2M
|
-$9.74M
|
-746,328
|
-31%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$15.9M
|
+$4.8M
|
+367,898
|
+40%
|
|
|
17
|
Deerfield Management
New York
|
$15.6M
|
–
|
–
|
–
|
|
|
18
|
Boxer Capital
San Diego,
California
|
$14.6M
|
–
|
–
|
–
|
|
|
19
|
TimesSquare Capital Management
New York
|
$14M
|
+$4.39M
|
+336,910
|
+42%
|
|
|
20
|
Adage Capital Partners
Boston,
Massachusetts
|
$12.7M
|
-$18.3M
|
-1,405,901
|
-58%
|
|
|
21
|
Baker Bros. Advisors
New York
|
$12.3M
|
–
|
–
|
–
|
|
|
22
|
Janus Henderson Group
London,
|
$10.1M
|
+$1.75M
|
+133,943
|
+19%
|
|
|
23
|
Commodore Capital
New York
|
$9.08M
|
–
|
–
|
–
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$7.36M
|
+$7.83M
|
+600,039
|
New
|
|
|
25
|
DAFNA Capital Management
Los Angeles,
California
|
$7.2M
|
+$1.04M
|
+79,363
|
+16%
|
|
