We are live on ! Find out more
CRSP icon

CRISPR Therapeutics

433 hedge funds and large institutions have $3.52B invested in CRISPR Therapeutics in 2025 Q2 according to their latest regulatory filings, with 101 funds opening new positions, 127 increasing their positions, 101 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

68% more first-time investments, than exits

New positions opened: 101 | Existing positions closed: 60

60% more capital invested

Capital invested by funds: $2.2B → $3.52B (+$1.32B)

31% more call options, than puts

Call options by funds: $244M | Put options by funds: $186M

26% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 101

9% more funds holding

Funds holding: 396433 (+37)

8.4% more ownership

Funds ownership: 75.39%83.79% (+8.4%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

Holders
433
Holders Change
+37
Holders Change %
+9.34%
% of All Funds
5.7%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
101
Increased
127
Reduced
101
Closed
60
Calls
$244M
Puts
$186M
Net Calls
+$58.2M
Net Calls Change
+$37.5M
Name Holding Trade Value Shares
Change
Change in
Stake
William Blair & Company
101
William Blair & Company
Illinois
$1.71M -$1.28M -33,087 -49%
Janus Henderson Group
102
Janus Henderson Group
United Kingdom
$1.69M
CII
103
Capital International Inc
California
$1.54M -$1.54M -39,802 -56%
BIP
104
Bouvel Investment Partners
Pennsylvania
$1.52M +$366K +9,458 +44%
SPS
105
Susquehanna Portfolio Strategies
Pennsylvania
$1.51M +$463K +11,965 +63%
WHG
106
Westwood Holdings Group
Texas
$1.48M -$331K -8,552 -22%
Squarepoint
107
Squarepoint
New York
$1.47M -$1.65M -42,746 -59%
Jones Financial Companies
108
Jones Financial Companies
Missouri
$1.41M +$342K +8,828 +42%
Ensign Peak Advisors
109
Ensign Peak Advisors
Utah
$1.38M
New York State Common Retirement Fund
110
New York State Common Retirement Fund
New York
$1.27M +$966K +24,972 +2,034%
Verition Fund Management
111
Verition Fund Management
Connecticut
$1.25M -$2.26M -58,354 -69%
NRD
112
Nebula Research & Development
New York
$1.22M +$289K +7,469 +42%
Walleye Capital
113
Walleye Capital
New York
$1.22M -$5.16M -133,304 -84%
IIM
114
Ipswich Investment Management
Massachusetts
$1.21M +$16.4K +425 +2%
Mercer Global Advisors
115
Mercer Global Advisors
Colorado
$1.21M +$523K +13,512 +119%
HAM
116
Hedges Asset Management
Nevada
$1.2M -$180K -4,650 -16%
HWAM
117
Hennion & Walsh Asset Management
New Jersey
$1.19M -$602K -15,561 -39%
PA
118
Profund Advisors
Maryland
$1.18M -$180K -4,644 -16%
Zurich Cantonal Bank
119
Zurich Cantonal Bank
Switzerland
$1.17M +$40.1K +1,036 +4%
Handelsbanken Fonder
120
Handelsbanken Fonder
Sweden
$1.16M
ASRS
121
Arizona State Retirement System
Arizona
$1.16M +$25.4K +656 +3%
PFGIA
122
Patriot Financial Group Insurance Agency
Massachusetts
$1.13M +$17.4K +450 +2%
IMC Chicago
123
IMC Chicago
Illinois
$1.12M -$1.51M -39,134 -63%
CIA
124
Concurrent Investment Advisors
Florida
$1.12M +$889K +22,967 New
TRCT
125
Tower Research Capital (TRC)
New York
$1.09M -$73K -1,886 -8%

CRSP Hedge Fund Activity: Q2 2025 in Review

433 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q2 2025, worth a combined $3.52B — up 60% from $2.2B a quarter earlier.

Buyers outnumbered sellers: 101 funds opened new CRSP positions and 60 closed out — a net gain of 41 holders — while 127 added to existing stakes and 101 trimmed.

The largest buyer was BlackRock, adding an estimated $134M. The largest seller was UBS AM, cutting an estimated $38.2M.

  • 433 institutional investors held CRISPR Therapeutics (CRSP) as of Q2 2025, up from 396 in Q1 2025.
  • Funds reported $3.52B of CRISPR Therapeutics stock for Q2 2025, up 60% quarter-over-quarter.
  • 101 funds opened new CRISPR Therapeutics positions in Q2 2025 and 60 closed out, a net change of +41 holders.
  • The largest CRISPR Therapeutics buyer in Q2 2025 was BlackRock, an estimated $134M added.
  • The largest CRISPR Therapeutics seller in Q2 2025 was UBS AM, an estimated $38.2M sold.

Based on aggregated 13F filings for Q2 2025.