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CRISPR Therapeutics

396 hedge funds and large institutions have $2.2B invested in CRISPR Therapeutics in 2025 Q1 according to their latest regulatory filings, with 55 funds opening new positions, 123 increasing their positions, 102 reducing their positions, and 59 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more funds holding in top 10

Funds holding in top 10: 46 (+2)

27% more call options, than puts

Call options by funds: $96.3M | Put options by funds: $75.6M

21% more repeat investments, than reductions

Existing positions increased: 123 | Existing positions reduced: 102

0.25% less ownership

Funds ownership: 75.64%75.39% (-0.25%)

7% less first-time investments, than exits

New positions opened: 55 | Existing positions closed: 59

2% less funds holding

Funds holding: 404396 (-8)

13% less capital invested

Capital invested by funds: $2.54B → $2.2B (-$339M)

Holders
396
Holders Change
-8
Holders Change %
-1.98%
% of All Funds
5.31%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
55
Increased
123
Reduced
102
Closed
59
Calls
$96.3M
Puts
$75.6M
Net Calls
+$20.7M
Net Calls Change
+$30.7M
Name Holding Trade Value Shares
Change
Change in
Stake
TI
101
Trexquant Investment
Connecticut
$1.32M +$1.65M +38,831 New
Janus Henderson Group
102
Janus Henderson Group
United Kingdom
$1.29M
Asset Management One
103
Asset Management One
Japan
$1.22M
Walleye Trading
104
Walleye Trading
New York
$1.14M +$1.42M +33,453 New
HighTower Advisors
105
HighTower Advisors
Illinois
$1.12M +$56.2K +1,325 +4%
KOC
106
Koss-Olinger Consulting
Florida
$1.11M -$70.2K -1,656 -5%
TC
107
TwinBeech Capital
New York
$1.07M +$1.34M +31,578 New
BIP
108
Bouvel Investment Partners
Pennsylvania
$1.02M -$6.06K -143 -0.7%
HAM
109
Hedges Asset Management
Nevada
$999K +$212K +5,000 +21%
SG Americas Securities
110
SG Americas Securities
New York
$998K +$349K +8,240 +39%
PA
111
Profund Advisors
Maryland
$984K -$64.7K -1,526 -5%
Ensign Peak Advisors
112
Ensign Peak Advisors
Utah
$969K
Invesco
113
Invesco
Georgia
$951K -$247K -5,833 -17%
T. Rowe Price Associates
114
T. Rowe Price Associates
Maryland
$932K +$119K +2,800 +11%
Nomura Holdings
115
Nomura Holdings
Japan
$905K +$1.13M +26,596 New
AF
116
Avanza Fonder
Sweden
$866K +$1.07M +25,341 New
AQR Capital Management
117
AQR Capital Management
Connecticut
$861K +$1.07M +25,306 New
VRS
118
Virginia Retirement Systems
Virginia
$848K +$1.06M +24,930 New
IIM
119
Ipswich Investment Management
Massachusetts
$835K -$31.6K -745 -3%
TRCT
120
Tower Research Capital (TRC)
New York
$829K +$801K +18,902 +347%
Handelsbanken Fonder
121
Handelsbanken Fonder
Sweden
$813K -$21.2K -500 -2%
ASRS
122
Arizona State Retirement System
Arizona
$790K -$10.6K -251 -1%
Zurich Cantonal Bank
123
Zurich Cantonal Bank
Switzerland
$786K +$37.1K +876 +4%
Wolverine Trading
124
Wolverine Trading
Illinois
$780K -$1.21M -28,466 -57%
Jones Financial Companies
125
Jones Financial Companies
Missouri
$775K +$410K +9,678 +86%

CRSP Hedge Fund Activity: Q1 2025 in Review

396 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q1 2025, worth a combined $2.2B — down 13% from $2.54B a quarter earlier.

Sellers outnumbered buyers: 59 funds closed out of CRSP and 55 opened new positions — a net loss of 4 holders — while 102 trimmed existing stakes and 123 added.

The largest buyer was UBS AM, adding an estimated $53.5M. The largest seller was Capital International Investors, cutting an estimated $113M.

  • 396 institutional investors held CRISPR Therapeutics (CRSP) as of Q1 2025, down from 404 in Q4 2024.
  • Funds reported $2.2B of CRISPR Therapeutics stock for Q1 2025, down 13% quarter-over-quarter.
  • 55 funds opened new CRISPR Therapeutics positions in Q1 2025 and 59 closed out, a net change of -4 holders.
  • The largest CRISPR Therapeutics buyer in Q1 2025 was UBS AM, an estimated $53.5M added.
  • The largest CRISPR Therapeutics seller in Q1 2025 was Capital International Investors, an estimated $113M sold.

Based on aggregated 13F filings for Q1 2025.