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CRISPR Therapeutics

479 hedge funds and large institutions have $4.03B invested in CRISPR Therapeutics in 2025 Q4 according to their latest regulatory filings, with 95 funds opening new positions, 151 increasing their positions, 127 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more first-time investments, than exits

New positions opened: 95 | Existing positions closed: 52

35% more call options, than puts

Call options by funds: $233M | Put options by funds: $172M

19% more repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 127

9% more funds holding

Funds holding: 440479 (+39)

0.82% more ownership

Funds ownership: 79.43%80.26% (+0.82%)

14% less capital invested

Capital invested by funds: $4.68B → $4.03B (-$657M)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

Holders
479
Holders Change
+39
Holders Change %
+8.86%
% of All Funds
5.83%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.07%
New
95
Increased
151
Reduced
127
Closed
52
Calls
$233M
Puts
$172M
Net Calls
+$61M
Net Calls Change
+$25M
Name Holding Trade Value Shares
Change
Change in
Stake
CAM
76
Congress Asset Management
Massachusetts
$3.32M -$286K -4,774 -7%
Invesco
77
Invesco
Georgia
$3.19M -$271K -4,531 -7%
Osaic Holdings
78
Osaic Holdings
Arizona
$3.1M +$196K +3,276 +6%
Jones Financial Companies
79
Jones Financial Companies
Missouri
$3.01M +$765K +12,774 +29%
EWA
80
EverSource Wealth Advisors
Alabama
$3.01M -$2.39M -39,969 -41%
GC
81
Guggenheim Capital
Illinois
$2.99M -$26.4K -440 -0.8%
Envestnet Asset Management
82
Envestnet Asset Management
Illinois
$2.97M -$827K -13,817 -20%
GAA
83
Green Alpha Advisors
Colorado
$2.92M +$43.4K +725 +1%
CI
84
Capital International
California
$2.91M -$361K -6,033 -10%
BEI
85
Benjamin Edwards Inc
Missouri
$2.87M +$24.9K +416 +0.8%
First Trust Advisors
86
First Trust Advisors
Illinois
$2.85M +$3.25M +54,325 New
National Bank of Canada
87
National Bank of Canada
Quebec, Canada
$2.81M +$2.62M +43,704 +445%
Stifel Financial
88
Stifel Financial
Missouri
$2.74M +$816K +13,630 +35%
CRC
89
Curi RMB Capital
Illinois
$2.65M -$53.4K -892 -2%
Lazard Asset Management
90
Lazard Asset Management
New York
$2.63M -$484K -8,080 -14%
State of Wisconsin Investment Board
91
State of Wisconsin Investment Board
Wisconsin
$2.53M -$209K -3,495 -7%
MIM
92
MetLife Investment Management
New Jersey
$2.52M -$13.4K -224 -0.5%
DekaBank Deutsche Girozentrale
93
DekaBank Deutsche Girozentrale
Germany
$2.4M
Cambridge Investment Research Advisors
94
Cambridge Investment Research Advisors
Iowa
$2.33M -$130K -2,179 -5%
PFM
95
Privium Fund Management
Netherlands
$2.25M +$172K +2,874 +7%
Manulife (Manufacturers Life Insurance)
96
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.18M -$28.7K -480 -1%
PAI
97
Palo Alto Investors
California
$2.16M
QCM
98
Qsemble Capital Management
New York
$2.13M +$2.43M +40,586 New
State of New Jersey Common Pension Fund D
99
State of New Jersey Common Pension Fund D
New Jersey
$2.12M +$4.07K +68 +0.2%
Tudor Investment Corp
100
Tudor Investment Corp
Connecticut
$2.07M +$2.36M +39,468 New