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CRISPR Therapeutics

433 hedge funds and large institutions have $3.52B invested in CRISPR Therapeutics in 2025 Q2 according to their latest regulatory filings, with 101 funds opening new positions, 127 increasing their positions, 101 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

68% more first-time investments, than exits

New positions opened: 101 | Existing positions closed: 60

60% more capital invested

Capital invested by funds: $2.2B → $3.52B (+$1.32B)

31% more call options, than puts

Call options by funds: $244M | Put options by funds: $186M

26% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 101

9% more funds holding

Funds holding: 396433 (+37)

8.4% more ownership

Funds ownership: 75.39%83.79% (+8.4%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

Holders
433
Holders Change
+37
Holders Change %
+9.34%
% of All Funds
5.7%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
101
Increased
127
Reduced
101
Closed
60
Calls
$244M
Puts
$186M
Net Calls
+$58.2M
Net Calls Change
+$37.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Lazard Asset Management
76
Lazard Asset Management
New York
$2.88M -$169K -4,357 -7%
GC
77
Guggenheim Capital
Illinois
$2.84M -$1.46M -37,778 -39%
GAA
78
Green Alpha Advisors
Colorado
$2.84M +$42.6K +1,102 +2%
BEI
79
Benjamin Edwards Inc
Missouri
$2.81M +$265K +6,845 +13%
Deutsche Bank
80
Deutsche Bank
Germany
$2.79M +$1.9M +49,013 +594%
Osaic Holdings
81
Osaic Holdings
Arizona
$2.53M +$324K +8,372 +19%
State of Wisconsin Investment Board
82
State of Wisconsin Investment Board
Wisconsin
$2.51M -$30.4K -785 -1%
CRC
83
Curi RMB Capital
Illinois
$2.5M +$162K +4,187 +9%
PTC
84
Philadelphia Trust Company
Pennsylvania
$2.44M +$1.94M +50,250 New
State of New Jersey Common Pension Fund D
85
State of New Jersey Common Pension Fund D
New Jersey
$2.44M +$335K +8,645 +21%
MIM
86
MetLife Investment Management
New Jersey
$2.4M +$1.91M +49,339 New
HighTower Advisors
87
HighTower Advisors
Illinois
$2.39M +$625K +16,163 +49%
Cetera Investment Advisers
88
Cetera Investment Advisers
Illinois
$2.34M -$383K -9,904 -17%
Cambridge Investment Research Advisors
89
Cambridge Investment Research Advisors
Iowa
$2.21M +$243K +6,278 +16%
PAI
90
Palo Alto Investors
California
$2.17M +$1.73M +44,625 New
PFM
91
Privium Fund Management
Netherlands
$2.17M -$596K -15,397 -26%
Stifel Financial
92
Stifel Financial
Missouri
$2.09M +$152K +3,931 +10%
KOC
93
Koss-Olinger Consulting
Florida
$2.05M +$375K +9,685 +30%
DekaBank Deutsche Girozentrale
94
DekaBank Deutsche Girozentrale
Germany
$2.01M
Manulife (Manufacturers Life Insurance)
95
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.91M +$1.1M +28,410 +261%
YIH
96
Y-Intercept (HK)
Hong Kong
$1.9M +$1.52M +39,161 New
IIM
97
INTECH Investment Management
Florida
$1.9M +$1.51M +38,983 New
SG Americas Securities
98
SG Americas Securities
New York
$1.87M +$354K +9,141 +31%
VOYA Investment Management
99
VOYA Investment Management
Georgia
$1.77M +$870K +22,481 +162%
Asset Management One
100
Asset Management One
Japan
$1.75M

CRSP Hedge Fund Activity: Q2 2025 in Review

433 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q2 2025, worth a combined $3.52B — up 60% from $2.2B a quarter earlier.

Buyers outnumbered sellers: 101 funds opened new CRSP positions and 60 closed out — a net gain of 41 holders — while 127 added to existing stakes and 101 trimmed.

The largest buyer was BlackRock, adding an estimated $134M. The largest seller was UBS AM, cutting an estimated $38.2M.

  • 433 institutional investors held CRISPR Therapeutics (CRSP) as of Q2 2025, up from 396 in Q1 2025.
  • Funds reported $3.52B of CRISPR Therapeutics stock for Q2 2025, up 60% quarter-over-quarter.
  • 101 funds opened new CRISPR Therapeutics positions in Q2 2025 and 60 closed out, a net change of +41 holders.
  • The largest CRISPR Therapeutics buyer in Q2 2025 was BlackRock, an estimated $134M added.
  • The largest CRISPR Therapeutics seller in Q2 2025 was UBS AM, an estimated $38.2M sold.

Based on aggregated 13F filings for Q2 2025.