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CRISPR Therapeutics

396 hedge funds and large institutions have $2.2B invested in CRISPR Therapeutics in 2025 Q1 according to their latest regulatory filings, with 55 funds opening new positions, 123 increasing their positions, 102 reducing their positions, and 59 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more funds holding in top 10

Funds holding in top 10: 46 (+2)

27% more call options, than puts

Call options by funds: $96.3M | Put options by funds: $75.6M

21% more repeat investments, than reductions

Existing positions increased: 123 | Existing positions reduced: 102

0.25% less ownership

Funds ownership: 75.64%75.39% (-0.25%)

7% less first-time investments, than exits

New positions opened: 55 | Existing positions closed: 59

2% less funds holding

Funds holding: 404396 (-8)

13% less capital invested

Capital invested by funds: $2.54B → $2.2B (-$339M)

Holders
396
Holders Change
-8
Holders Change %
-1.98%
% of All Funds
5.31%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
55
Increased
123
Reduced
102
Closed
59
Calls
$96.3M
Puts
$75.6M
Net Calls
+$20.7M
Net Calls Change
+$30.7M
Name Holding Trade Value Shares
Change
Change in
Stake
CI
76
Capital International
California
$2.45M -$2.39M -56,317 -44%
CII
77
Capital International Inc
California
$2.43M -$1.18M -27,845 -28%
California State Teachers Retirement System (CalSTRS)
78
California State Teachers Retirement System (CalSTRS)
California
$2.37M
CAM
79
Congress Asset Management
Massachusetts
$2.32M -$18.5K -437 -0.6%
William Blair & Company
80
William Blair & Company
Illinois
$2.32M -$1.96M -46,183 -40%
Envestnet Asset Management
81
Envestnet Asset Management
Illinois
$2.32M +$510K +12,025 +21%
SC
82
Slow Capital
California
$2.22M +$156K +3,669 +6%
IEFM
83
IQ EQ Fund Management
Ireland
$2.22M +$1.23M +28,931 +80%
PEAK6
84
PEAK6
Illinois
$2.17M +$2.7M +63,749 New
Lazard Asset Management
85
Lazard Asset Management
New York
$2.17M -$311K -7,333 -10%
IMC Chicago
86
IMC Chicago
Illinois
$2.12M -$1.03M -24,255 -28%
SFI
87
Susquehanna Fundamental Investments
Pennsylvania
$2.06M -$1.35M -31,860 -34%
PFM
88
Privium Fund Management
Netherlands
$2.05M +$1.06M +25,100 +72%
Cetera Investment Advisers
89
Cetera Investment Advisers
Illinois
$1.97M +$1.19M +28,084 +94%
GAA
90
Green Alpha Advisors
Colorado
$1.95M +$1.39M +32,732 +133%
State of Wisconsin Investment Board
91
State of Wisconsin Investment Board
Wisconsin
$1.78M +$1.23K +29 +0.1%
Tudor Investment Corp
92
Tudor Investment Corp
Connecticut
$1.74M +$1.39M +32,905 +179%
BEI
93
Benjamin Edwards Inc
Missouri
$1.73M +$248K +5,853 +13%
CRC
94
Curi RMB Capital
Illinois
$1.61M -$77.6K -1,831 -4%
Osaic Holdings
95
Osaic Holdings
Arizona
$1.49M -$265K -6,253 -13%
State of New Jersey Common Pension Fund D
96
State of New Jersey Common Pension Fund D
New Jersey
$1.41M -$134K -3,152 -7%
HWAM
97
Hennion & Walsh Asset Management
New Jersey
$1.36M -$184K -4,348 -10%
Cambridge Investment Research Advisors
98
Cambridge Investment Research Advisors
Iowa
$1.33M +$208K +4,914 +14%
WHG
99
Westwood Holdings Group
Texas
$1.33M -$595K -14,036 -26%
Stifel Financial
100
Stifel Financial
Missouri
$1.33M -$174K -4,109 -10%

CRSP Hedge Fund Activity: Q1 2025 in Review

396 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q1 2025, worth a combined $2.2B — down 13% from $2.54B a quarter earlier.

Sellers outnumbered buyers: 59 funds closed out of CRSP and 55 opened new positions — a net loss of 4 holders — while 102 trimmed existing stakes and 123 added.

The largest buyer was UBS AM, adding an estimated $53.5M. The largest seller was Capital International Investors, cutting an estimated $113M.

  • 396 institutional investors held CRISPR Therapeutics (CRSP) as of Q1 2025, down from 404 in Q4 2024.
  • Funds reported $2.2B of CRISPR Therapeutics stock for Q1 2025, down 13% quarter-over-quarter.
  • 55 funds opened new CRISPR Therapeutics positions in Q1 2025 and 59 closed out, a net change of -4 holders.
  • The largest CRISPR Therapeutics buyer in Q1 2025 was UBS AM, an estimated $53.5M added.
  • The largest CRISPR Therapeutics seller in Q1 2025 was Capital International Investors, an estimated $113M sold.

Based on aggregated 13F filings for Q1 2025.