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CRISPR Therapeutics

396 hedge funds and large institutions have $2.2B invested in CRISPR Therapeutics in 2025 Q1 according to their latest regulatory filings, with 55 funds opening new positions, 123 increasing their positions, 102 reducing their positions, and 59 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more funds holding in top 10

Funds holding in top 10: 46 (+2)

27% more call options, than puts

Call options by funds: $96.3M | Put options by funds: $75.6M

21% more repeat investments, than reductions

Existing positions increased: 123 | Existing positions reduced: 102

0.25% less ownership

Funds ownership: 75.64%75.39% (-0.25%)

7% less first-time investments, than exits

New positions opened: 55 | Existing positions closed: 59

2% less funds holding

Funds holding: 404396 (-8)

13% less capital invested

Capital invested by funds: $2.54B → $2.2B (-$339M)

Holders
396
Holders Change
-8
Holders Change %
-1.98%
% of All Funds
5.31%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
55
Increased
123
Reduced
102
Closed
59
Calls
$96.3M
Puts
$75.6M
Net Calls
+$20.7M
Net Calls Change
+$30.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Nordea Investment Management
51
Nordea Investment Management
Sweden
$4.31M +$50.9K +1,200 +1%
PAG
52
Private Advisor Group
New Jersey
$3.69M +$991K +23,382 +27%
CIS
53
Capital International Sarl
California
$3.5M -$3.56M -83,978 -45%
RMCM
54
Reynders McVeigh Capital Management
Massachusetts
$3.46M +$173K +4,086 +4%
ACM
55
Aquatic Capital Management
Illinois
$3.38M +$2.19M +51,690 +108%
GC
56
Guggenheim Capital
Illinois
$3.28M +$384K +9,065 +10%
California Public Employees Retirement System
57
California Public Employees Retirement System
California
$3.25M -$14K -331 -0.3%
Wealth Enhancement Advisory Services
58
Wealth Enhancement Advisory Services
Minnesota
$3.2M +$2.83M +66,789 +245%
HCS
59
Himension Capital (Singapore)
Singapore
$3.18M +$543K +12,804 +16%
CRB
60
Chad R. Baker
$3.17M
ECM
61
ExodusPoint Capital Management
New York
$3.11M +$1.84M +43,463 +91%
HF
62
HRT Financial
New York
$3.09M +$3.49M +82,277 +953%
Rockefeller Capital Management
63
Rockefeller Capital Management
New York
$3.08M +$39.5K +931 +1%
Barclays
64
Barclays
United Kingdom
$3.05M -$527K -12,432 -12%
Raymond James Financial
65
Raymond James Financial
Florida
$2.95M +$194K +4,571 +6%
EWA
66
EverSource Wealth Advisors
Alabama
$2.89M +$3.59M +84,708 +49,249%
Verition Fund Management
67
Verition Fund Management
Connecticut
$2.86M +$1.57M +37,020 +79%
Balyasny Asset Management
68
Balyasny Asset Management
Illinois
$2.84M -$34.4M -810,468 -91%
VanEck Associates
69
VanEck Associates
New York
$2.83M
DekaBank Deutsche Girozentrale
70
DekaBank Deutsche Girozentrale
Germany
$2.81M
Legal & General Group
71
Legal & General Group
United Kingdom
$2.76M -$706K -16,649 -17%
Bank of New York Mellon
72
Bank of New York Mellon
New York
$2.64M +$48K +1,133 +1%
Mirae Asset Global ETFs Holdings
73
Mirae Asset Global ETFs Holdings
Hong Kong
$2.58M -$196K -4,634 -6%
Commonwealth Equity Services
74
Commonwealth Equity Services
Massachusetts
$2.55M +$266K +6,268 +9%
Squarepoint
75
Squarepoint
New York
$2.49M -$3.95M -93,115 -56%

CRSP Hedge Fund Activity: Q1 2025 in Review

396 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q1 2025, worth a combined $2.2B — down 13% from $2.54B a quarter earlier.

Sellers outnumbered buyers: 59 funds closed out of CRSP and 55 opened new positions — a net loss of 4 holders — while 102 trimmed existing stakes and 123 added.

The largest buyer was UBS AM, adding an estimated $53.5M. The largest seller was Capital International Investors, cutting an estimated $113M.

  • 396 institutional investors held CRISPR Therapeutics (CRSP) as of Q1 2025, down from 404 in Q4 2024.
  • Funds reported $2.2B of CRISPR Therapeutics stock for Q1 2025, down 13% quarter-over-quarter.
  • 55 funds opened new CRISPR Therapeutics positions in Q1 2025 and 59 closed out, a net change of -4 holders.
  • The largest CRISPR Therapeutics buyer in Q1 2025 was UBS AM, an estimated $53.5M added.
  • The largest CRISPR Therapeutics seller in Q1 2025 was Capital International Investors, an estimated $113M sold.

Based on aggregated 13F filings for Q1 2025.