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CRISPR Therapeutics

479 hedge funds and large institutions have $4.03B invested in CRISPR Therapeutics in 2025 Q4 according to their latest regulatory filings, with 95 funds opening new positions, 151 increasing their positions, 127 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more first-time investments, than exits

New positions opened: 95 | Existing positions closed: 52

35% more call options, than puts

Call options by funds: $233M | Put options by funds: $172M

19% more repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 127

9% more funds holding

Funds holding: 440479 (+39)

0.82% more ownership

Funds ownership: 79.43%80.26% (+0.82%)

14% less capital invested

Capital invested by funds: $4.68B → $4.03B (-$657M)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

Holders
479
Holders Change
+39
Holders Change %
+8.86%
% of All Funds
5.83%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.07%
New
95
Increased
151
Reduced
127
Closed
52
Calls
$233M
Puts
$172M
Net Calls
+$61M
Net Calls Change
+$25M
Name Holding Trade Value Shares
Change
Change in
Stake
Norges Bank
26
Norges Bank
Norway
$25.7M +$29.4M +490,206 New
Two Sigma Investments
27
Two Sigma Investments
New York
$24.7M -$34.4M -574,068 -55%
IEFM
28
IQ EQ Fund Management
Ireland
$20.4M +$6.37M +106,408 +38%
Wells Fargo
29
Wells Fargo
California
$16.7M +$940K +15,700 +5%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$16.3M +$380K +6,347 +2%
Ameriprise
31
Ameriprise
Minnesota
$15.6M -$876K -14,619 -5%
Goldman Sachs
32
Goldman Sachs
New York
$14.5M +$2.52M +42,090 +18%
Citadel Advisors
33
Citadel Advisors
Florida
$14M +$6.02M +100,584 +60%
AF
34
Align Financial
Minnesota
$13.1M +$785K +13,110 New
Barclays
35
Barclays
United Kingdom
$13.1M -$5.98M -99,863 -29%
VAS
36
Vestmark Advisory Solutions
Massachusetts
$13.1M +$634K +10,586 +4%
N
37
Nuveen
North Carolina
$9.62M +$32.5K +543 +0.3%
Pictet Asset Management
38
Pictet Asset Management
Switzerland
$9.02M -$1.5M -25,129 -13%
LPL Financial
39
LPL Financial
California
$8.96M -$2.41M -40,230 -19%
Raymond James Financial
40
Raymond James Financial
Florida
$8.77M +$3.43M +57,318 +52%
Royal Bank of Canada
41
Royal Bank of Canada
Ontario, Canada
$8.68M -$18M -300,605 -64%
Two Sigma Advisers
42
Two Sigma Advisers
New York
$8.52M -$24.6M -410,572 -72%
Swiss National Bank
43
Swiss National Bank
Switzerland
$8.47M +$144K +2,400 +2%
TD Asset Management
44
TD Asset Management
Ontario, Canada
$8.31M -$970K -16,200 -9%
CGH
45
Contrarius Group Holdings
Bermuda
$8.21M -$6.81M -113,745 -42%
UBS AM
46
UBS AM
Illinois
$7.81M +$8.92M +148,901 New
VVM
47
Versant Venture Management
California
$7.8M
Citigroup
48
Citigroup
New York
$6.96M +$4.32M +72,204 +119%
MG
49
Marex Group
$6.69M +$226K +3,777 +3%
NSGL
50
No Street GP LP
California
$6.55M +$7.49M +125,000 New