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CRISPR Therapeutics

433 hedge funds and large institutions have $3.52B invested in CRISPR Therapeutics in 2025 Q2 according to their latest regulatory filings, with 101 funds opening new positions, 127 increasing their positions, 101 reducing their positions, and 60 closing their positions.

New
Increased
Maintained
Reduced
Closed

68% more first-time investments, than exits

New positions opened: 101 | Existing positions closed: 60

60% more capital invested

Capital invested by funds: $2.2B → $3.52B (+$1.32B)

31% more call options, than puts

Call options by funds: $244M | Put options by funds: $186M

26% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 101

9% more funds holding

Funds holding: 396433 (+37)

8.4% more ownership

Funds ownership: 75.39%83.79% (+8.4%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

Holders
433
Holders Change
+37
Holders Change %
+9.34%
% of All Funds
5.7%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
101
Increased
127
Reduced
101
Closed
60
Calls
$244M
Puts
$186M
Net Calls
+$58.2M
Net Calls Change
+$37.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$24.9M -$30.5M -788,602 -61%
VVM
27
Versant Venture Management
California
$24.2M
Bank of Montreal
28
Bank of Montreal
Ontario, Canada
$24M +$19.1M +493,743 New
VAS
29
Vestmark Advisory Solutions
Massachusetts
$23.6M +$10M +259,669 +115%
Norges Bank
30
Norges Bank
Norway
$19.8M -$1.92M -49,573 -11%
Barclays
31
Barclays
United Kingdom
$18.5M +$11.3M +290,997 +325%
CGH
32
Contrarius Group Holdings
Bermuda
$18.2M +$1.66M +42,982 +13%
JF
33
Jump Financial
Illinois
$17.3M +$13.8M +356,306 New
Royal Bank of Canada
34
Royal Bank of Canada
Ontario, Canada
$16.4M +$7.52M +194,442 +136%
JP Morgan Chase
35
JP Morgan Chase
New York
$15.6M +$972K +25,107 +8%
Bank of New York Mellon
36
Bank of New York Mellon
New York
$14.7M +$8.68M +224,257 +289%
Ameriprise
37
Ameriprise
Minnesota
$12.7M +$1.7M +44,029 +20%
Wells Fargo
38
Wells Fargo
California
$11.5M -$1.15M -29,786 -11%
Pictet Asset Management
39
Pictet Asset Management
Switzerland
$11.2M -$393K -10,166 -4%
TD Asset Management
40
TD Asset Management
Ontario, Canada
$11.1M -$538K -13,904 -6%
Goldman Sachs
41
Goldman Sachs
New York
$10.7M +$2.84M +73,272 +50%
IEFM
42
IQ EQ Fund Management
Ireland
$9.51M +$5.05M +130,407 +200%
LPL Financial
43
LPL Financial
California
$9.46M +$353K +9,121 +5%
N
44
Nuveen
North Carolina
$8.99M +$7.15M +184,853 New
Swiss National Bank
45
Swiss National Bank
Switzerland
$7.61M -$27.1K -700 -0.4%
WP
46
Woodline Partners
California
$7.26M +$495K +12,784 +9%
Legal & General Group
47
Legal & General Group
United Kingdom
$6.3M +$1.87M +48,412 +60%
Nordea Investment Management
48
Nordea Investment Management
Sweden
$6.25M +$34.8K +900 +0.7%
Citigroup
49
Citigroup
New York
$6.17M -$3.05M -78,756 -38%
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$6.03M +$4.79M +123,893 New

CRSP Hedge Fund Activity: Q2 2025 in Review

433 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q2 2025, worth a combined $3.52B — up 60% from $2.2B a quarter earlier.

Buyers outnumbered sellers: 101 funds opened new CRSP positions and 60 closed out — a net gain of 41 holders — while 127 added to existing stakes and 101 trimmed.

The largest buyer was BlackRock, adding an estimated $134M. The largest seller was UBS AM, cutting an estimated $38.2M.

  • 433 institutional investors held CRISPR Therapeutics (CRSP) as of Q2 2025, up from 396 in Q1 2025.
  • Funds reported $3.52B of CRISPR Therapeutics stock for Q2 2025, up 60% quarter-over-quarter.
  • 101 funds opened new CRISPR Therapeutics positions in Q2 2025 and 60 closed out, a net change of +41 holders.
  • The largest CRISPR Therapeutics buyer in Q2 2025 was BlackRock, an estimated $134M added.
  • The largest CRISPR Therapeutics seller in Q2 2025 was UBS AM, an estimated $38.2M sold.

Based on aggregated 13F filings for Q2 2025.