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CRISPR Therapeutics

396 hedge funds and large institutions have $2.2B invested in CRISPR Therapeutics in 2025 Q1 according to their latest regulatory filings, with 55 funds opening new positions, 123 increasing their positions, 102 reducing their positions, and 59 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more funds holding in top 10

Funds holding in top 10: 46 (+2)

27% more call options, than puts

Call options by funds: $96.3M | Put options by funds: $75.6M

21% more repeat investments, than reductions

Existing positions increased: 123 | Existing positions reduced: 102

0.25% less ownership

Funds ownership: 75.64%75.39% (-0.25%)

7% less first-time investments, than exits

New positions opened: 55 | Existing positions closed: 59

2% less funds holding

Funds holding: 404396 (-8)

13% less capital invested

Capital invested by funds: $2.54B → $2.2B (-$339M)

Holders
396
Holders Change
-8
Holders Change %
-1.98%
% of All Funds
5.31%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
55
Increased
123
Reduced
102
Closed
59
Calls
$96.3M
Puts
$75.6M
Net Calls
+$20.7M
Net Calls Change
+$30.7M
Name Holding Trade Value Shares
Change
Change in
Stake
DSC
376
Duncker Streett & Co
Missouri
$374
CFFP
377
Center for Financial Planning
Michigan
$341
PWMG
378
Private Wealth Management Group
New Jersey
$341
SC
379
Stephens Consulting
Michigan
$341
CSB
380
City State Bank
Iowa
$340
FDCP
381
Foster Dykema Cabot & Partners
Massachusetts
$340
HWM
382
HighMark Wealth Management
Minnesota
$340
Amundi
383
Amundi
France
$294
CFS
384
Compass Financial Services
Iowa
$238
NSG
385
Nalls Sherbakoff Group
Tennessee
$238 +$297 +7 New
BTI
386
Blue Trust Inc
Georgia
$204
AA
387
Addison Advisors
Vermont
$171
LWMI
388
Legacy Wealth Management (Idaho)
Idaho
$137
SWC
389
Spectrum Wealth Counsel
Indiana
$137
FPF
390
First Pacific Financial
Washington
$137 +$170 +4 New
RF
391
Robbins Farley
New Hampshire
$103
FFA
392
Frazier Financial Advisors
Ohio
$69
JFA
393
JNBA Financial Advisors
Minnesota
$69
NB
394
NBT Bank
New York
$68
T
395
Transce3nd
Texas
$68
VWM
396
Valley Wealth Managers
New Jersey
$8
AC
397
Armistice Capital
New York
-$8.19M -208,000 Closed
JF
398
Jump Financial
Illinois
-$5.48M -139,280 Closed
Simplex Trading
399
Simplex Trading
Illinois
-$3.52M -83,134 Closed
CCP
400
Clough Capital Partners
Massachusetts
-$2.25M -57,200 Closed

CRSP Hedge Fund Activity: Q1 2025 in Review

396 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in CRISPR Therapeutics (CRSP) for Q1 2025, worth a combined $2.2B — down 13% from $2.54B a quarter earlier.

Sellers outnumbered buyers: 59 funds closed out of CRSP and 55 opened new positions — a net loss of 4 holders — while 102 trimmed existing stakes and 123 added.

The largest buyer was UBS AM, adding an estimated $53.5M. The largest seller was Capital International Investors, cutting an estimated $113M.

  • 396 institutional investors held CRISPR Therapeutics (CRSP) as of Q1 2025, down from 404 in Q4 2024.
  • Funds reported $2.2B of CRISPR Therapeutics stock for Q1 2025, down 13% quarter-over-quarter.
  • 55 funds opened new CRISPR Therapeutics positions in Q1 2025 and 59 closed out, a net change of -4 holders.
  • The largest CRISPR Therapeutics buyer in Q1 2025 was UBS AM, an estimated $53.5M added.
  • The largest CRISPR Therapeutics seller in Q1 2025 was Capital International Investors, an estimated $113M sold.

Based on aggregated 13F filings for Q1 2025.