|
1
|
RA Capital Management
Boston,
Massachusetts
|
$322M
|
–
|
–
|
–
|
|
|
2
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$289M
|
+$33.2M
|
+520,310
|
+21%
|
|
|
3
|
Point72 Asset Management
Stamford,
Connecticut
|
$151M
|
+$3.2M
|
+50,139
|
+3%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$135M
|
+$40.1M
|
+627,773
|
+80%
|
|
|
5
|
Vivo Capital
Palo Alto,
California
|
$126M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$118M
|
+$16.8M
|
+263,961
|
+27%
|
|
|
7
|
|
$112M
|
+$3.69M
|
+57,785
|
+5%
|
|
|
8
|
Darwin Global Management
St. Helier,
Jersey
|
$95M
|
+$14.6M
|
+228,772
|
+30%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$92M
|
+$61.3M
|
+961,164
|
New
|
|
|
10
|
|
$90.7M
|
+$19.6M
|
+307,700
|
+48%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$74.3M
|
+$42.6M
|
+666,815
|
+613%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$74M
|
+$34.2M
|
+535,822
|
+226%
|
|
|
13
|
Janus Henderson Group
London,
|
$65.4M
|
+$3.69M
|
+57,901
|
+9%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$56.9M
|
+$19.3M
|
+303,042
|
+104%
|
|
|
15
|
Commodore Capital
New York
|
$56M
|
-$37.6M
|
-590,000
|
-50%
|
|
|
16
|
Farallon Capital Management
San Francisco,
California
|
$48.6M
|
+$19.7M
|
+308,000
|
+154%
|
|
|
17
|
Fred Alger Management
New York
|
$48.2M
|
+$32.1M
|
+502,877
|
New
|
|
|
18
|
Soleus Capital Management
Greenwich,
Connecticut
|
$47.3M
|
+$1.98M
|
+31,000
|
+7%
|
|
|
19
|
Holocene Advisors
New York
|
$46.7M
|
+$31.1M
|
+487,233
|
New
|
|
|
20
|
UBS Group
Zurich,
Switzerland
|
$45.3M
|
+$18.9M
|
+295,644
|
+166%
|
|
|
21
|
Adage Capital Partners
Boston,
Massachusetts
|
$43.1M
|
-$41.5M
|
-650,000
|
-59%
|
|
|
22
|
Maverick Capital
Dallas,
Texas
|
$40M
|
+$26.6M
|
+417,550
|
New
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$38.7M
|
+$2.05M
|
+32,104
|
+9%
|
|
|
24
|
Vestal Point Capital
New York
|
$38.3M
|
-$6.38M
|
-100,000
|
-20%
|
|
|
25
|
Jennison Associates
New York
|
$37.9M
|
+$22.1M
|
+346,803
|
+705%
|
|
