|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$33.7M
|
-$823K
|
-2,741
|
-3%
|
|
|
2
|
Frazier Management
Seattle,
Washington
|
$22.5M
|
+$19.7M
|
+65,613
|
New
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$20.1M
|
-$95.5K
|
-318
|
-0.5%
|
|
|
4
|
|
$17.5M
|
–
|
–
|
–
|
|
|
5
|
Perceptive Advisors
New York
|
$12.7M
|
–
|
–
|
–
|
|
|
6
|
|
$9.37M
|
+$3.22M
|
+10,716
|
+65%
|
|
|
7
|
BB Biotech
Schaffhausen,
Switzerland
|
$8.01M
|
+$7.01M
|
+23,334
|
New
|
|
|
8
|
Eventide Asset Management
Boston,
Massachusetts
|
$4.53M
|
+$1.33M
|
+4,430
|
+51%
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$4.29M
|
-$375K
|
-1,250
|
-9%
|
|
|
10
|
Broadfin Capital
New York
|
$2.86M
|
–
|
–
|
–
|
|
|
11
|
AWM Investment Company
New York
|
$2.57M
|
+$264K
|
+880
|
+13%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.31M
|
+$516K
|
+1,718
|
+34%
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$2.23M
|
+$17.1K
|
+57
|
+0.9%
|
|
|
14
|
Deerfield Management
New York
|
$2.05M
|
-$1.77M
|
-5,906
|
-50%
|
|
|
15
|
Putnam Investments
Boston,
Massachusetts
|
$1.72M
|
–
|
–
|
–
|
|
|
16
|
Tekla Capital Management
Boston,
Massachusetts
|
$901K
|
+$37.5K
|
+125
|
+5%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$860K
|
+$46.8K
|
+156
|
+7%
|
|
|
18
|
UBS O'Connor
Chicago,
Illinois
|
$686K
|
-$394K
|
-1,311
|
-40%
|
|
|
19
|
BlackRock Institutional Trust
San Francisco,
California
|
$614K
|
+$29.1K
|
+97
|
+6%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$582K
|
+$58.6K
|
+195
|
+13%
|
|
|
21
|
Spark Investment Management
New York
|
$564K
|
+$494K
|
+1,645
|
New
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$453K
|
+$71.5K
|
+238
|
+22%
|
|
|
23
|
Nationwide Fund Advisors
Columbus,
Ohio
|
$293K
|
–
|
–
|
–
|
|
|
24
|
BlackRock Investment Management
Wilmington,
Delaware
|
$291K
|
-$44.1K
|
-147
|
-15%
|
|
|
25
|
|
$290K
|
+$254K
|
+846
|
New
|
|
