|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$21.9M
|
-$2.78M
|
-12,077
|
-12%
|
|
|
2
|
Frazier Management
Seattle,
Washington
|
$16.7M
|
–
|
–
|
–
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$14.9M
|
–
|
–
|
–
|
|
|
4
|
|
$12.9M
|
–
|
–
|
–
|
|
|
5
|
BB Biotech
Schaffhausen,
Switzerland
|
$9.48M
|
+$3.23M
|
+14,007
|
+60%
|
|
|
6
|
Perceptive Advisors
New York
|
$9.43M
|
–
|
–
|
–
|
|
|
7
|
|
$3.49M
|
-$3.12M
|
-13,559
|
-50%
|
|
|
8
|
AWM Investment Company
New York
|
$3.37M
|
+$1.33M
|
+5,750
|
+77%
|
|
|
9
|
Eventide Asset Management
Boston,
Massachusetts
|
$3.35M
|
–
|
–
|
–
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$3.17M
|
–
|
–
|
–
|
|
|
11
|
Broadfin Capital
New York
|
$2.12M
|
–
|
–
|
–
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.06M
|
+$319K
|
+1,386
|
+21%
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$1.56M
|
-$82.3K
|
-357
|
-5%
|
|
|
14
|
Putnam Investments
Boston,
Massachusetts
|
$1.27M
|
–
|
–
|
–
|
|
|
15
|
Tekla Capital Management
Boston,
Massachusetts
|
$921K
|
+$230K
|
+1,000
|
+38%
|
|
|
16
|
Deerfield Management
New York
|
$873K
|
-$584K
|
-2,534
|
-42%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$638K
|
+$922
|
+4
|
+0.2%
|
|
|
18
|
Sabby Management
Miami Beach,
Florida
|
$512K
|
+$464K
|
+2,014
|
New
|
|
|
19
|
UBS O'Connor
Chicago,
Illinois
|
$498K
|
-$8.76K
|
-38
|
-2%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$475K
|
+$40.3K
|
+175
|
+10%
|
|
|
21
|
BlackRock Institutional Trust
San Francisco,
California
|
$437K
|
-$15.9K
|
-69
|
-4%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$343K
|
+$6.68K
|
+29
|
+2%
|
|
|
23
|
BlackRock Investment Management
Wilmington,
Delaware
|
$219K
|
+$3.92K
|
+17
|
+2%
|
|
|
24
|
Nationwide Fund Advisors
Columbus,
Ohio
|
$217K
|
–
|
–
|
–
|
|
|
25
|
Bank of New York Mellon
New York
|
$208K
|
+$922
|
+4
|
+0.5%
|
|
