|
1
|
BB Biotech
Schaffhausen,
Switzerland
|
$10.1M
|
–
|
–
|
–
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$8.49M
|
–
|
–
|
–
|
|
|
3
|
Omega Fund Management
Boston,
Massachusetts
|
$6.64M
|
–
|
–
|
–
|
|
|
4
|
InterWest Venture Management
San Francisco,
California
|
$5.97M
|
–
|
–
|
–
|
|
|
5
|
Frazier Management
Seattle,
Washington
|
$5.77M
|
–
|
–
|
–
|
|
|
6
|
Opaleye Management
Boston,
Massachusetts
|
$5.28M
|
–
|
–
|
–
|
|
|
7
|
|
$4.49M
|
–
|
–
|
–
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$3.96M
|
-$2.52M
|
-28,609
|
-39%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.91M
|
+$379K
|
+4,299
|
+15%
|
|
|
10
|
Stonepine Capital Management
Bend,
Oregon
|
$2.89M
|
+$1.02M
|
+11,530
|
+54%
|
|
|
11
|
Monashee Investment Management
Boston,
Massachusetts
|
$2.12M
|
–
|
–
|
–
|
|
|
12
|
Granahan Investment Management
Waltham,
Massachusetts
|
$2.11M
|
+$107K
|
+1,207
|
+5%
|
|
|
13
|
Alethea Capital Management
Mercer Island,
Washington
|
$1.92M
|
+$1.45M
|
+16,413
|
+301%
|
|
|
14
|
Millennium Management
New York
|
$1.92M
|
-$1.26M
|
-14,288
|
-40%
|
|
|
15
|
Prosight Management
Dallas,
Texas
|
$1.43M
|
-$3.68M
|
-41,690
|
-72%
|
|
|
16
|
Fosun International
Hong Kong,
China
|
$1.36M
|
+$1.35M
|
+15,334
|
New
|
|
|
17
|
Renaissance Technologies
New York
|
$1.36M
|
+$108K
|
+1,220
|
+9%
|
|
|
18
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$1.32M
|
–
|
–
|
–
|
|
|
19
|
|
$1.26M
|
-$91.5K
|
-1,037
|
-7%
|
|
|
20
|
Raymond James & Associates
St Petersburg,
Florida
|
$1.05M
|
+$194K
|
+2,196
|
+22%
|
|
|
21
|
DAFNA Capital Management
Los Angeles,
California
|
$936K
|
–
|
–
|
–
|
|
|
22
|
Raymond James Financial Services Advisors
St. Petersburg,
Florida
|
$935K
|
+$194K
|
+2,197
|
+26%
|
|
|
23
|
West Family Investments
Carlsbad,
California
|
$880K
|
+$203K
|
+2,306
|
+30%
|
|
|
24
|
Bridgeway Capital Management
Houston,
Texas
|
$788K
|
+$375K
|
+4,250
|
+90%
|
|
|
25
|
Tekla Capital Management
Boston,
Massachusetts
|
$699K
|
–
|
–
|
–
|
|
