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C4 Therapeutics
CCCC

Name Holding Trade Value Shares
Change 		Change in
Stake
PAMU
26
Pictet Asset Management (UK)
United Kingdom
$5.43M +$4.75M +163,771 New
IC
27
Ikarian Capital
Texas
$5.02M +$4.39M +151,500 New
SCM
28
Suvretta Capital Management
New York
$4.75M +$4.16M +143,482 New
ACM
29
Asymmetry Capital Management
California
$4.62M +$4.04M +139,343 New
Northern Trust
30
Northern Trust
Illinois
$4.14M +$3.63M +125,070 New
MS
31
Maven Securities
Jersey
$3.65M +$2.95M +101,692 New
ACP
32
Acuta Capital Partners
California
$3.64M +$3.19M +110,000 New
LCM
33
Laurion Capital Management
New York
$3.63M +$3.18M +109,600 New
Citadel Advisors
34
Citadel Advisors
Florida
$3.44M +$3.01M +103,873 New
UBS Group
35
UBS Group
Switzerland
$3.34M +$2.92M +100,716 New
Charles Schwab
36
Charles Schwab
California
$2.21M +$1.94M +66,742 New
CC
37
Casdin Capital
New York
$1.32M +$1.16M +40,000 New
Ensign Peak Advisors
38
Ensign Peak Advisors
Utah
$1.32M +$1.16M +40,000 New
PAWC
39
P.A.W. Capital
Connecticut
$1.32M +$1.16M +40,000 New
Wells Fargo
40
Wells Fargo
California
$1.28M +$1.12M +38,527 New
Bank of New York Mellon
41
Bank of New York Mellon
New York
$939K +$822K +28,341 New
Nuveen
42
Nuveen
North Carolina
$816K +$714K +24,624 New
California Public Employees Retirement System
43
California Public Employees Retirement System
California
$707K +$619K +21,329 New
AAA
44
Affinity Asset Advisors
New York
$663K +$580K +20,000 New
BPC
45
Banque Pictet & Cie
Switzerland
$663K +$580K +20,000 New
Vontobel Holding
46
Vontobel Holding
Switzerland
$663K +$580K +20,000 New
ZP
47
Zimmer Partners
New York
$663K +$580K +20,000 New
CSS
48
Cubist Systematic Strategies
Connecticut
$662K +$580K +19,994 New
BFM
49
Boothbay Fund Management
New York
$537K +$470K +16,204 New
California State Teachers Retirement System (CalSTRS)
50
California State Teachers Retirement System (CalSTRS)
California
$535K +$468K +16,140 New
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