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Axsome Therapeutics
AXSM

Overview Fund Activity

349 hedge funds and large institutions have $4.32B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 91 funds opening new positions, 101 increasing their positions, 114 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
349
Holders Change
+59
Holders Change %
+20.34%
% of All Funds
4.74%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
91
Increased
101
Reduced
114
Closed
29
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M

Top Buyers

1
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$72.7M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$61.5M
3
O
OrbiMed
New York
+$45.1M
4
1832 Asset Management
1832 Asset Management
Ontario, Canada
+$42.4M
5
Man Group
Man Group
United Kingdom
+$40.8M

Top Sellers

1
RI
RTW Investments
New York
-$132M
2
RCM
RA Capital Management
Massachusetts
-$84.6M
3
FFM
Fairmount Funds Management
Pennsylvania
-$76.3M
4
Lazard Asset Management
Lazard Asset Management
New York
-$59.3M
5
HRCM
Hood River Capital Management
Florida
-$54.6M
Name Holding Trade Value Shares
Change 		Shares
Change %
HRCM
351
Hood River Capital Management
Florida
– -$54.6M -644,785 Closed
BCM
352
Boxer Capital Management
California
– -$39.8M -470,000 Closed
Norges Bank
353
Norges Bank
Norway
– -$34.1M -403,026 Closed
CC
354
Checkpoint Capital
California
– -$14.8M -174,769 Closed
CM
355
Caption Management
Oklahoma
– -$9.79M -115,686 Closed
MB
356
MPM BioImpact
Massachusetts
– -$4.23M -50,000 Closed
JFG
357
Jefferies Financial Group
New York
– -$3.44M -40,700 Closed
BHCM
358
Brevan Howard Capital Management
Jersey
– -$3.28M -38,748 Closed
ACM
359
ADAR1 Capital Management
Texas
– -$1.66M -19,661 Closed
TI
360
Trexquant Investment
Connecticut
– -$1.2M -14,129 Closed
Calamos Advisors
361
Calamos Advisors
Illinois
– -$1.08M -12,808 Closed
Hudson Bay Capital Management
362
Hudson Bay Capital Management
Connecticut
– -$1.06M -12,500 Closed
1CM
363
1492 Capital Management
Wisconsin
– -$963K -11,385 Closed
BC
364
Bridgefront Capital
Texas
– -$893K -10,555 Closed
PTC
365
Petrus Trust Company
Texas
– -$742K -8,764 Closed
SCM
366
Superstring Capital Management
New York
– -$361K -4,268 Closed
SPA
367
Sherbrooke Park Advisers
New York
– -$345K -4,082 Closed
SSWG
368
Seven Springs Wealth Group
Tennessee
– -$339K -4,005 Closed
VEA
369
Virtus ETF Advisers
New York
– -$313K -3,705 Closed
1C
370
111 Capital
France
– -$278K -3,291 Closed
FCC
371
Flower City Capital
New York
– -$254K -3,000 Closed
Simplex Trading
372
Simplex Trading
Illinois
– -$248K -2,942 Closed
Corient Private Wealth
373
Corient Private Wealth
Florida
– -$239K -2,829 Closed
Nomura Holdings
374
Nomura Holdings
Japan
– -$212K -2,500 Closed
RS
375
R Squared
Hong Kong
– -$64.3K -760 Closed
12 13 14
15
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