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Axsome Therapeutics
AXSM

Overview Fund Activity

349 hedge funds and large institutions have $4.32B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 91 funds opening new positions, 101 increasing their positions, 114 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
349
Holders Change
+59
Holders Change %
+20.34%
% of All Funds
4.74%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
91
Increased
101
Reduced
114
Closed
29
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M

Top Buyers

1
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$72.7M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$61.5M
3
O
OrbiMed
New York
+$45.1M
4
1832 Asset Management
1832 Asset Management
Ontario, Canada
+$42.4M
5
Man Group
Man Group
United Kingdom
+$40.8M

Top Sellers

1
RI
RTW Investments
New York
-$132M
2
RCM
RA Capital Management
Massachusetts
-$84.6M
3
FFM
Fairmount Funds Management
Pennsylvania
-$76.3M
4
Lazard Asset Management
Lazard Asset Management
New York
-$59.3M
5
HRCM
Hood River Capital Management
Florida
-$54.6M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fifth Third Bancorp
301
Fifth Third Bancorp
Ohio
$23.3K – – –
SAM
302
Smartleaf Asset Management
Massachusetts
$22.4K +$830 +7 +4%
GI
303
GAMMA Investing
California
$22K +$15.4K +132 +232%
HNB
304
Huntington National Bank
Ohio
$21.6K -$3.38K -29 -14%
Daiwa Securities Group
305
Daiwa Securities Group
Japan
$19K – – –
T
306
Transce3nd
Texas
$17.5K +$1.87K +16 +12%
MPWT
307
MassMutual Private Wealth & Trust
Connecticut
$16.1K +$15.4K +132 +2,200%
QCG
308
Quadrant Capital Group
Ohio
$15.7K – – –
C
309
Covestor
United Kingdom
$15K +$117 +1 +0.8%
CCM
310
Coldstream Capital Management
Washington
$14K +$14K +120 New
UB
311
UMB Bank
Missouri
$13.8K – – –
BTI
312
Blue Trust Inc
Georgia
$13.2K – – –
HCM
313
Hollencrest Capital Management
California
$10.1K +$10.1K +87 New
RA
314
Rise Advisors
New York
$9.33K +$9.33K +80 New
GWM
315
Geneos Wealth Management
Colorado
$7.93K +$3.25K +16 +70%
AAP
316
Arax Advisory Partners
Colorado
$7.81K +$5.72K +49 +272%
WA
317
WPG Advisers
Maryland
$7.11K +$2.45K +21 +53%
RIL
318
Rothschild Investment LLC
Illinois
$7K +$2.92K +25 +71%
HI
319
Harbour Investments
Wisconsin
$7K +$4.2K +36 +150%
Optiver Holding
320
Optiver Holding
Netherlands
$7K +$7K +60 New
OCM
321
Orion Capital Management
California
$5.83K – – –
PTC
322
Private Trust Company
Ohio
$4.78K -$933 -8 -16%
PA
323
PSI Advisors
Florida
$4.67K – – –
SCM
324
Sterling Capital Management
North Carolina
$4.43K +$117 +1 +3%
FFA
325
Farther Finance Advisors
California
$4.36K -$335 -3 -7%
11 12
13
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