AXSM icon

Axsome Therapeutics
AXSM

Overview Fund Activity

349 hedge funds and large institutions have $4.32B invested in Axsome Therapeutics in 2025 Q1 according to their latest regulatory filings, with 91 funds opening new positions, 101 increasing their positions, 114 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
349
Holders Change
+59
Holders Change %
+20.34%
% of All Funds
4.74%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.16%
New
91
Increased
101
Reduced
114
Closed
29
Calls
$111M
Puts
$86.5M
Net Calls
+$24.5M
Net Calls Change
-$35M

Top Buyers

1
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$72.7M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$61.5M
3
O
OrbiMed
New York
+$45.1M
4
1832 Asset Management
1832 Asset Management
Ontario, Canada
+$42.4M
5
Man Group
Man Group
United Kingdom
+$40.8M

Top Sellers

1
RI
RTW Investments
New York
-$132M
2
RCM
RA Capital Management
Massachusetts
-$84.6M
3
FFM
Fairmount Funds Management
Pennsylvania
-$76.3M
4
Lazard Asset Management
Lazard Asset Management
New York
-$59.3M
5
HRCM
Hood River Capital Management
Florida
-$54.6M
Name Holding Trade Value Shares
Change 		Shares
Change %
MCP
226
Mirador Capital Partners
California
$467K – – –
AWM
227
Aries Wealth Management
Maine
$467K – – –
PA
228
Profund Advisors
Maryland
$453K -$117K -1,003 -21%
GCP
229
GSA Capital Partners
United Kingdom
$452K +$452K +3,873 New
JMFC
230
J.M. Forbes & Co
Massachusetts
$448K – – –
VIA
231
Virtus Investment Advisers
Connecticut
$444K +$444K +3,806 New
AIP
232
Ameritas Investment Partners
Nebraska
$437K -$12K -103 -3%
Public Employees Retirement Association of Colorado
233
Public Employees Retirement Association of Colorado
Colorado
$432K – – –
ONSWM
234
Old North State Wealth Management
North Carolina
$402K – – –
XT
235
XTX Topco
Cayman Islands
$392K -$1.14M -9,794 -74%
Pathstone Holdings
236
Pathstone Holdings
New Jersey
$379K -$29.6K -254 -7%
Canada Life
237
Canada Life
Manitoba, Canada
$364K – – –
CAPTRUST Financial Advisors
238
CAPTRUST Financial Advisors
North Carolina
$362K +$17.6K +151 +5%
OSAM
239
O'Shaughnessy Asset Management
Connecticut
$362K +$362K +3,104 New
IB
240
Intrust Bank
Kansas
$361K +$31.5K +270 +10%
VA
241
Vident Advisory
Georgia
$360K +$360K +3,083 New
SP
242
SIH Partners
Delaware
$358K +$358K +3,071 New
X
243
Xponance
Pennsylvania
$337K +$27.1K +232 +9%
CC
244
Centiva Capital
New York
$329K +$329K +2,820 New
SG Americas Securities
245
SG Americas Securities
New York
$321K -$93.5K -801 -23%
PWM
246
Prosperity Wealth Management
California
$321K +$321K +2,750 New
Rafferty Asset Management
247
Rafferty Asset Management
New York
$318K -$105K -901 -25%
Russell Investments Group
248
Russell Investments Group
United Kingdom
$308K -$1.96M -16,799 -86%
CAU
249
Caxton Associates (UK)
$307K +$307K +2,629 New
Mackenzie Financial
250
Mackenzie Financial
Ontario, Canada
$273K +$273K +2,339 New
8 9
10
11 12