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Axsome Therapeutics
AXSM

Overview Fund Activity

341 hedge funds and large institutions have $3.95B invested in Axsome Therapeutics in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 151 increasing their positions, 89 reducing their positions, and 57 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
341
Holders Change
-8
Holders Change %
-2.29%
% of All Funds
4.57%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
54
Increased
151
Reduced
89
Closed
57
Calls
$66.7M
Puts
$69.3M
Net Calls
-$2.59M
Net Calls Change
-$27.1M

Top Buyers

1
DTC
1
Deep Track Capital
Connecticut
$83.7M
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$64M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$46.7M
4
HRCM
4
Hood River Capital Management
Florida
$38.7M
5
BlackRock
5
BlackRock
New York
$400M

Top Sellers

1
RI
1
RTW Investments
New York
$158M
2
Assenagon Asset Management
2
Assenagon Asset Management
Luxembourg
$18.9M
3
1832 Asset Management
3
1832 Asset Management
Ontario, Canada
$0
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$21M
5
Invesco
5
Invesco
Georgia
$59.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
MCP
226
Mirador Capital Partners
California
$418K – – –
AWM
227
Aries Wealth Management
Maine
$418K – – –
TRCT
228
Tower Research Capital (TRC)
New York
$405K +$313K +2,999 +340%
MAM
229
Martingale Asset Management
Massachusetts
$397K +$397K +3,801 New
Public Employees Retirement Association of Colorado
230
Public Employees Retirement Association of Colorado
Colorado
$387K – – –
JMFC
231
J.M. Forbes & Co
Massachusetts
$387K -$14.2K -136 -4%
ONSWM
232
Old North State Wealth Management
North Carolina
$360K – – –
Comerica Bank
233
Comerica Bank
Texas
$354K -$291K -2,792 -45%
Pathstone Holdings
234
Pathstone Holdings
New Jersey
$341K +$1.04K +10 +0.3%
Polen Capital Management
235
Polen Capital Management
Florida
$337K +$337K +3,232 New
X
236
Xponance
Pennsylvania
$329K +$27.5K +263 +9%
Carson Wealth (CWM LLC)
237
Carson Wealth (CWM LLC)
Nebraska
$314K +$127K +1,218 +68%
IB
238
Intrust Bank
Kansas
$300K -$22.8K -218 -7%
Osaic Holdings
239
Osaic Holdings
Arizona
$292K +$162K +1,693 +125%
SC
240
SummitTX Capital
Texas
$283K +$283K +2,709 New
QCM
241
Qsemble Capital Management
New York
$280K +$280K +2,681 New
NS
242
NBC Securities
Alabama
$272K +$244K +2,337 +856%
QL
243
Quarry LP
New York
$261K +$115K +1,100 +79%
JFG
244
Jefferies Financial Group
New York
$261K +$261K +2,500 New
SSA
245
Schonfeld Strategic Advisors
New York
$260K -$2.27M -21,710 -90%
BRWA
246
B. Riley Wealth Advisors
Florida
$258K +$258K +2,471 New
LOAMU
247
Lombard Odier Asset Management (USA)
New York
$251K +$251K +2,406 New
MYIA
248
Mount Yale Investment Advisors
Colorado
$247K +$247K +2,366 New
MC
249
Moors & Cabot
Massachusetts
$243K +$10.4K +100 +4%
NIM
250
NEOS Investment Management
Connecticut
$243K – – –
8 9
10
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