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Ascendis Pharma A/S

247 hedge funds and large institutions have $10.9B invested in Ascendis Pharma A/S in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 82 increasing their positions, 88 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 1416 (+2)

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B → $10.9B (+$708M)

1% more funds holding

Funds holding: 244247 (+3)

7% less repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 88

4.51% less ownership

Funds ownership: 107.4%102.88% (-4.5%)

Holders
247
Holders Change
+3
Holders Change %
+1.23%
% of All Funds
3.25%
Holding in Top 10
16
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+14.29%
% of All Funds
0.21%
New
44
Increased
82
Reduced
88
Closed
40
Calls
$39.2M
Puts
$12.6M
Net Calls
+$26.6M
Net Calls Change
+$41.1M
Name Holding Trade Value Shares
Change
Change in
Stake
FAM
151
Fred Alger Management
New York
$655K -$9.94M -61,011 -94%
Daiwa Securities Group
152
Daiwa Securities Group
Japan
$645K +$242K +1,488 +66%
CPIG
153
Chicago Partners Investment Group
Illinois
$635K +$26.2K +161 +5%
SAM
154
Sectoral Asset Management
Quebec, Canada
$599K +$225K +1,380 +66%
Cetera Investment Advisers
155
Cetera Investment Advisers
Illinois
$552K +$521K +3,200 New
Mercer Global Advisors
156
Mercer Global Advisors
Colorado
$540K +$510K +3,128 New
Two Sigma Investments
157
Two Sigma Investments
New York
$538K -$2.55M -15,646 -83%
TWC
158
TD Waterhouse Canada
Ontario, Canada
$525K +$33.2K +204 +7%
QL
159
Quarry LP
New York
$518K -$48.9K -300 -9%
HS
160
HighVista Strategies
Massachusetts
$513K -$505K -3,098 -51%
GAM
161
Groupama Asset Management
France
$506K
Corient Private Wealth
162
Corient Private Wealth
Florida
$498K -$83.2K -511 -15%
DAS
163
Diversify Advisory Services
Utah
$482K +$76.1K +467 +23%
Polen Capital Management
164
Polen Capital Management
Florida
$469K +$443K +2,719 New
NIP
165
Nicholas Investment Partners
California
$455K +$430K +2,637 New
Walleye Trading
166
Walleye Trading
New York
$450K -$217K -1,330 -34%
VIA
167
Virtus Investment Advisers
Connecticut
$449K -$23.9K -147 -5%
ACM
168
Aquatic Capital Management
Illinois
$417K -$4.58M -28,093 -92%
AssetMark Inc
169
AssetMark Inc
California
$410K +$376K +2,309 +3,346%
ProShare Advisors
170
ProShare Advisors
Maryland
$391K -$74.8K -459 -17%
LJAC
171
L.J. Altfest & Co
New York
$375K +$10.3K +63 +3%
AG
172
Algert Global
California
$375K -$60.9K -374 -15%
SSA
173
Schonfeld Strategic Advisors
New York
$323K -$9.53M -58,504 -97%
Mariner
174
Mariner
Kansas
$309K -$17.9K -110 -6%
LCM
175
Legato Capital Management
California
$302K

ASND Hedge Fund Activity: Q2 2025 in Review

247 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q2 2025, worth a combined $10.9B — up 7% from $10.1B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ASND positions and 40 closed out — a net gain of 4 holders — while 82 added to existing stakes and 88 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $157M. The largest seller was Morgan Stanley, cutting an estimated $269M.

  • 247 institutional investors held Ascendis Pharma A/S (ASND) as of Q2 2025, up from 244 in Q1 2025.
  • Funds reported $10.9B of Ascendis Pharma A/S stock for Q2 2025, up 7% quarter-over-quarter.
  • 44 funds opened new Ascendis Pharma A/S positions in Q2 2025 and 40 closed out, a net change of +4 holders.
  • The largest Ascendis Pharma A/S buyer in Q2 2025 was Perceptive Advisors, an estimated $157M added.
  • The largest Ascendis Pharma A/S seller in Q2 2025 was Morgan Stanley, an estimated $269M sold.

Based on aggregated 13F filings for Q2 2025.