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Ascendis Pharma A/S

247 hedge funds and large institutions have $10.9B invested in Ascendis Pharma A/S in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 82 increasing their positions, 88 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 1416 (+2)

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B → $10.9B (+$708M)

1% more funds holding

Funds holding: 244247 (+3)

7% less repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 88

4.51% less ownership

Funds ownership: 107.4%102.88% (-4.5%)

Holders
247
Holders Change
+3
Holders Change %
+1.23%
% of All Funds
3.25%
Holding in Top 10
16
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+14.29%
% of All Funds
0.21%
New
44
Increased
82
Reduced
88
Closed
40
Calls
$39.2M
Puts
$12.6M
Net Calls
+$26.6M
Net Calls Change
+$41.1M
Name Holding Trade Value Shares
Change
Change in
Stake
CIBC Private Wealth Group
126
CIBC Private Wealth Group
Georgia
$1.45M
DWM
127
Diversify Wealth Management
Utah
$1.4M +$187K +1,145 +19%
PNC Financial Services Group
128
PNC Financial Services Group
Pennsylvania
$1.33M -$143K -877 -10%
AWM
129
Avior Wealth Management
Nebraska
$1.31M
LPL Financial
130
LPL Financial
California
$1.25M +$617K +3,787 +109%
D.E. Shaw & Co
131
D.E. Shaw & Co
New York
$1.24M -$2.17M -13,340 -65%
Ohio Public Employees Retirement System (OPERS)
132
Ohio Public Employees Retirement System (OPERS)
Ohio
$1.21M -$57K -350 -5%
GC
133
Gilbert & Cook
Iowa
$1.17M +$21.3K +131 +2%
AI
134
AdvisorShares Investments
Maryland
$1.13M +$1.06M +6,518 New
CM
135
Caption Management
Oklahoma
$1.12M -$3.18M -19,501 -75%
GC
136
Guggenheim Capital
Illinois
$1.08M -$133K -819 -12%
XT
137
XTX Topco
Cayman Islands
$1.05M +$378K +2,320 +62%
Mirae Asset Global Investments
138
Mirae Asset Global Investments
South Korea
$1.04M -$173K -1,062 -15%
MMEA
139
Main Management ETF Advisors
California
$1.01M +$15.6K +96 +2%
Creative Planning
140
Creative Planning
Kansas
$929K +$284K +1,746 +48%
CGH
141
Crossmark Global Holdings
Texas
$927K -$78.2K -480 -8%
Squarepoint
142
Squarepoint
New York
$897K +$847K +5,197 New
BFM
143
Boothbay Fund Management
New York
$823K +$777K +4,770 New
AI
144
Atria Investments
North Carolina
$762K +$321K +1,971 +81%
DnB Asset Management
145
DnB Asset Management
Norway
$728K -$125K -770 -15%
SPC
146
Sigma Planning Corp
Michigan
$708K +$422K +2,589 +171%
NIM
147
NEOS Investment Management
Connecticut
$704K -$330K -2,028 -33%
TE
148
Tema ETFs
New York
$704K -$330K -2,028 -33%
YIH
149
Y-Intercept (HK)
Hong Kong
$682K +$644K +3,951 New
CGIM
150
Capital Group Investment Management
Singapore
$670K

ASND Hedge Fund Activity: Q2 2025 in Review

247 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q2 2025, worth a combined $10.9B — up 7% from $10.1B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ASND positions and 40 closed out — a net gain of 4 holders — while 82 added to existing stakes and 88 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $157M. The largest seller was Morgan Stanley, cutting an estimated $269M.

  • 247 institutional investors held Ascendis Pharma A/S (ASND) as of Q2 2025, up from 244 in Q1 2025.
  • Funds reported $10.9B of Ascendis Pharma A/S stock for Q2 2025, up 7% quarter-over-quarter.
  • 44 funds opened new Ascendis Pharma A/S positions in Q2 2025 and 40 closed out, a net change of +4 holders.
  • The largest Ascendis Pharma A/S buyer in Q2 2025 was Perceptive Advisors, an estimated $157M added.
  • The largest Ascendis Pharma A/S seller in Q2 2025 was Morgan Stanley, an estimated $269M sold.

Based on aggregated 13F filings for Q2 2025.