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Ascendis Pharma A/S

279 hedge funds and large institutions have $12.7B invested in Ascendis Pharma A/S in 2025 Q3 according to their latest regulatory filings, with 56 funds opening new positions, 99 increasing their positions, 92 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

216% more call options, than puts

Call options by funds: $124M | Put options by funds: $39.3M

155% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 22

17% more capital invested

Capital invested by funds: $10.9B → $12.7B (+$1.83B)

13% more funds holding

Funds holding: 247279 (+32)

6% more funds holding in top 10

Funds holding in top 10: 1617 (+1)

8% more repeat investments, than reductions

Existing positions increased: 99 | Existing positions reduced: 92

0.65% more ownership

Funds ownership: 102.88%103.53% (+0.65%)

Holders
279
Holders Change
+32
Holders Change %
+12.96%
% of All Funds
3.66%
Holding in Top 10
17
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+6.25%
% of All Funds
0.22%
New
56
Increased
99
Reduced
92
Closed
22
Calls
$124M
Puts
$39.3M
Net Calls
+$84.9M
Net Calls Change
+$58.3M
Name Holding Trade Value Shares
Change
Change in
Stake
TI
101
Trexquant Investment
Connecticut
$5.48M -$6.82M -36,550 -57%
DP
102
Diadema Partners
New Jersey
$5.48M +$5.14M +27,572 New
Canada Pension Plan Investment Board
103
Canada Pension Plan Investment Board
Ontario, Canada
$5.27M +$4.95M +26,531 New
MC
104
Matisse Capital
Oregon
$5.17M -$358K -1,922 -7%
Brown Advisory
105
Brown Advisory
Maryland
$5.04M -$32.1K -172 -0.7%
Envestnet Asset Management
106
Envestnet Asset Management
Illinois
$4.96M +$603K +3,232 +15%
BG
107
Bellevue Group
Switzerland
$4.95M -$700K -3,752 -13%
SCM
108
Sterling Capital Management
North Carolina
$4.93M -$5.54M -29,725 -55%
ECM
109
ExodusPoint Capital Management
New York
$4.92M +$1.53M +8,178 +49%
SGA
110
Sector Gamma AS
Norway
$4.84M +$1.37M +7,327 +43%
HCA
111
Harbor Capital Advisors
Illinois
$4.57M -$10.4M -55,557 -71%
Citigroup
112
Citigroup
New York
$4.44M -$707K -3,788 -15%
ACM
113
Atika Capital Management
New York
$4.41M +$1.07M +5,760 +35%
CI
114
Capital International
California
$4.31M +$219K +1,174 +6%
Neuberger Berman Group
115
Neuberger Berman Group
New York
$4.18M -$408K -2,185 -9%
Stifel Financial
116
Stifel Financial
Missouri
$4.05M +$75.4K +404 +2%
SIA
117
Sit Investment Associates
Minnesota
$4M +$129K +690 +4%
KCM
118
Kennedy Capital Management
Missouri
$3.92M +$207K +1,111 +6%
EAM
119
Erste Asset Management
Austria
$3.89M
Marshall Wace
120
Marshall Wace
United Kingdom
$3.52M -$18.6M -99,464 -85%
HJIM
121
Henry James International Management
New York
$3.17M
RAM
122
Readystate Asset Management
Illinois
$3.1M -$15.9M -85,347 -85%
Northern Trust
123
Northern Trust
Illinois
$3.09M +$2.9M +15,557 New
ZP
124
Zimmer Partners
New York
$3.08M -$4.63M -24,800 -62%
ETCM
125
Evolutionary Tree Capital Management
Virginia
$3.05M -$580K -3,111 -17%

ASND Hedge Fund Activity: Q3 2025 in Review

279 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q3 2025, worth a combined $12.7B — up 17% from $10.9B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new ASND positions and 22 closed out — a net gain of 34 holders — while 99 added to existing stakes and 92 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $164M. The largest seller was T. Rowe Price Investment Management, cutting an estimated $171M.

  • 279 institutional investors held Ascendis Pharma A/S (ASND) as of Q3 2025, up from 247 in Q2 2025.
  • Funds reported $12.7B of Ascendis Pharma A/S stock for Q3 2025, up 17% quarter-over-quarter.
  • 56 funds opened new Ascendis Pharma A/S positions in Q3 2025 and 22 closed out, a net change of +34 holders.
  • The largest Ascendis Pharma A/S buyer in Q3 2025 was Wellington Management Group, an estimated $164M added.
  • The largest Ascendis Pharma A/S seller in Q3 2025 was T. Rowe Price Investment Management, an estimated $171M sold.

Based on aggregated 13F filings for Q3 2025.