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Ascendis Pharma A/S

247 hedge funds and large institutions have $10.9B invested in Ascendis Pharma A/S in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 82 increasing their positions, 88 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 1416 (+2)

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B → $10.9B (+$708M)

1% more funds holding

Funds holding: 244247 (+3)

7% less repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 88

4.51% less ownership

Funds ownership: 107.4%102.88% (-4.5%)

Holders
247
Holders Change
+3
Holders Change %
+1.23%
% of All Funds
3.25%
Holding in Top 10
16
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+14.29%
% of All Funds
0.21%
New
44
Increased
82
Reduced
88
Closed
40
Calls
$39.2M
Puts
$12.6M
Net Calls
+$26.6M
Net Calls Change
+$41.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Lazard Asset Management
76
Lazard Asset Management
New York
$9.08M +$1.55M +9,505 +22%
DT
77
Diversified Trust
Tennessee
$7.84M -$184K -1,130 -2%
PHP
78
Parkman Healthcare Partners
Connecticut
$7.27M +$6.86M +42,108 New
Walleye Capital
79
Walleye Capital
New York
$6.97M +$4M +24,566 +155%
ZP
80
Zimmer Partners
New York
$6.96M +$684K +4,200 +12%
SVCM
81
Saturn V Capital Management
Texas
$6.59M -$26.2M -161,073 -81%
O
82
OrbiMed
New York
$5.94M +$5.6M +34,400 New
VOYA Investment Management
83
VOYA Investment Management
Georgia
$5.75M +$2.55M +15,670 +89%
EF
84
Empowered Funds
Pennsylvania
$5.73M +$5.41M +33,196 New
Wells Fargo
85
Wells Fargo
California
$5.44M +$1.21M +7,410 +31%
TCA
86
Troluce Capital Advisors
Puerto Rico
$5.18M +$4.89M +30,000 New
DekaBank Deutsche Girozentrale
87
DekaBank Deutsche Girozentrale
Germany
$5.14M
Deutsche Bank
88
Deutsche Bank
Germany
$5.13M +$176K +1,080 +4%
Russell Investments Group
89
Russell Investments Group
United Kingdom
$5.07M +$916K +5,621 +24%
BG
90
Bellevue Group
Switzerland
$4.95M +$4.36M +26,755 +1,408%
CIS
91
Capital International Sarl
California
$4.86M +$453K +2,779 +11%
Principal Financial Group
92
Principal Financial Group
Iowa
$4.85M +$4.58M +28,116 New
MC
93
Matisse Capital
Oregon
$4.82M -$282K -1,732 -6%
Citigroup
94
Citigroup
New York
$4.5M +$804K +4,935 +23%
Nomura Asset Management
95
Nomura Asset Management
Japan
$4.43M +$707K +4,343 +20%
Brown Advisory
96
Brown Advisory
Maryland
$4.4M -$57.8K -355 -1%
Neuberger Berman Group
97
Neuberger Berman Group
New York
$4.01M -$3.76M -23,096 -50%
ACP
98
Acuta Capital Partners
California
$3.9M -$124K -764 -3%
Envestnet Asset Management
99
Envestnet Asset Management
Illinois
$3.75M +$1.61M +9,879 +83%
CI
100
Capital International
California
$3.54M +$48.4K +297 +1%

ASND Hedge Fund Activity: Q2 2025 in Review

247 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q2 2025, worth a combined $10.9B — up 7% from $10.1B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ASND positions and 40 closed out — a net gain of 4 holders — while 82 added to existing stakes and 88 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $157M. The largest seller was Morgan Stanley, cutting an estimated $269M.

  • 247 institutional investors held Ascendis Pharma A/S (ASND) as of Q2 2025, up from 244 in Q1 2025.
  • Funds reported $10.9B of Ascendis Pharma A/S stock for Q2 2025, up 7% quarter-over-quarter.
  • 44 funds opened new Ascendis Pharma A/S positions in Q2 2025 and 40 closed out, a net change of +4 holders.
  • The largest Ascendis Pharma A/S buyer in Q2 2025 was Perceptive Advisors, an estimated $157M added.
  • The largest Ascendis Pharma A/S seller in Q2 2025 was Morgan Stanley, an estimated $269M sold.

Based on aggregated 13F filings for Q2 2025.